Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550557 | 0.80 | CASP6 (0.62) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL24810184 | 0.79 | KMT2A (0.53) | NPC1RAB9AKMT2AMEN1CYP1A2 | |
| SCHEMBL24809081 | 0.78 | RAB9A (0.48) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL27982176 | 0.77 | RAB9A (0.66) | NPC1RAB9AKMT2AMEN1CYP1A2 | |
| SCHEMBL18773847 | 0.74 | KMT2A (0.77) | NPC1RAB9AKMT2AMEN1CYP1A2 | |
| SCHEMBL24809056 | 0.73 | RXFP1 (0.60) | NPC1RAB9AKMT2AMEN1CYP1A2 | |
| SCHEMBL34471875 | 0.73 | HDAC1 (0.54) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL21914836 | 0.73 | NPC1 (0.80) | NPC1RAB9AKMT2AMEN1CYP1A2 | |
| SCHEMBL4548770 | 0.71 | KDR (0.58) | KDRSIRT2SIRT1SIRT3 | |
| SCHEMBL29093258 | 0.71 | KDM4E (0.51) | RAB9AKMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022267941-A1 | ORGANOMETALLIC IRIDIUM COMPOUND | 广东阿格蕾雅光电材料有限公司 | 2022-12-29 | — | — | WO | disclosed |