Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27831990 | 0.82 | ADORA2A (0.33) | CPA1CPB2 | |
| SCHEMBL27850520 | 0.79 | ACHE (0.33) | CPA1CPB2 | |
| SCHEMBL12039663 | 0.77 | CPA1 (0.41) | CPA1CPB2 | |
| SCHEMBL20907767 | 0.74 | CPA1 (0.31) | CPA1CPB2 | |
| SCHEMBL23115030 | 0.74 | CPA1 (0.31) | CPA1CPB2 | |
| SCHEMBL27940974 | 0.74 | CPA1 (0.31) | CPA1CPB2 | |
| SCHEMBL20795402 | 0.70 | CYP2D6 (0.32) | — | |
| SCHEMBL20009013 | 0.67 | KDM5B (0.49) | — | |
| SCHEMBL824013 | 0.66 | — | — | |
| SCHEMBL27941105 | 0.66 | ACHE (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411426-A1 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411426-A1 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | IDE, SI, GPR119 | CPA1 731/4885CPB2 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.