SCHEMBL2480993

SCHEMBL2480993

CCCCCCCCCCC(O)CN[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GPR84 Q9NQS5 7/20 0.43
▸ TLR2 O60603 1/20 0.41
▸ NOD1 Q9Y239 3/20 0.40
▸ FAAH O00519 2/20 0.39
▸ FFAR1 O14842 2/20 0.39
▸ FFAR4 Q5NUL3 1/20 0.39
▸ SIRT6 Q8N6T7 1/20 0.39
▸ SIRT1 Q96EB6 1/20 0.39
▸ EPHX2 P34913 1/20 0.39
▸ FOLH1 Q04609 2/20 0.38
▸ LCK P06239 1/20 0.38
▸ PPARD Q03181 1/20 0.38
▸ ZDHHC20 Q5W0Z9 1/20 0.38
▸ ZDHHC2 Q9UIJ5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27859409 1.00 GPR84 (0.43) GPR84TLR2NOD1FAAHFFAR1
Hydrochloric Acid SCHEMBL6546097 0.99 GPR84 (0.42) GPR84TLR2NOD1FAAHFFAR1
Hydrochloric Acid SCHEMBL27456313 0.99 GPR84 (0.42) GPR84TLR2NOD1FAAHFFAR1
Hydrochloric Acid SCHEMBL27454617 0.99 GPR84 (0.42) GPR84TLR2NOD1FAAHFFAR1
Hydrochloric Acid SCHEMBL6546148 0.99 GPR84 (0.42) GPR84TLR2NOD1FAAHFFAR1
Hydrochloric Acid SCHEMBL7111708 0.99 GPR84 (0.42) GPR84TLR2NOD1FAAHFFAR1
SCHEMBL27455269 0.89 TLR2 (0.40) GPR84TLR2NOD1FFAR1SIRT6
SCHEMBL9219836 0.89 TLR2 (0.41) GPR84TLR2NOD1SIRT6SIRT1
SCHEMBL9219828 0.89 TLR2 (0.41) GPR84TLR2NOD1SIRT6SIRT1
Hydrochloric Acid SCHEMBL27457297 0.88 TLR2 (0.39) GPR84TLR2NOD1FFAR1SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102256936-B Arginine derivative and cosmetic comprising same NOF CORP 2014-06-18 — — CN disclosed
EP-2377848-B1 ARGININE DERIVATIVE AND COSMETIC COMPRISING SAME NOF CORP (JP) 2013-10-02 — — EP disclosed
US-8518994-B2 Arginine derivative and cosmetic containing the same NOF CORPORATION (JP) 2013-08-27 — — US disclosed
CN-102256936-A Arginine derivative and cosmetic comprising same NOF CORP 2011-11-23 — — CN disclosed
EP-2377848-A1 ARGININE DERIVATIVE AND COSMETIC COMPRISING SAME NOF Corporation (JP) 2011-10-19 — — EP disclosed
US-20110245344-A1 ARGININE DERIVATIVE AND COSMETIC CONTAINING THE SAME NOF CORPORATION (JP) 2011-10-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245344-A1 ARGININE DERIVATIVE AND COSMETIC CONTAINING THE SAME ARG1, ARG2, ARGLU1 GPR84 712/4885TLR2 1046/4885NOD1 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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