SCHEMBL2481089

SCHEMBL2481089

CC(O)CN[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 11/20 0.37
▸ NPY1R P25929 7/20 0.37
▸ NPY2R P49146 5/20 0.37
▸ NPY5R Q15761 5/20 0.37
▸ ITGB3 P05106 2/20 0.36
▸ ITGA2B P08514 2/20 0.36
▸ C3AR1 Q16581 1/20 0.36
▸ FOLH1 Q04609 1/20 0.34
▸ OTC P00480 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ GGT1 P19440 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9488991 1.00 NPY4R (0.37) NPY4RNPY1RNPY2RNPY5RITGB3
Hydrochloric Acid SCHEMBL27645702 0.97 NPY4R (0.36) NPY4RNPY1RNPY2RNPY5RITGB3
SCHEMBL14199862 0.90 NPY4R (0.40) NPY4RNPY1RNPY2RNPY5RITGB3
SCHEMBL2483025 0.86 C3AR1 (0.34) NPY4RNPY1RNPY2RNPY5RITGB3
SCHEMBL9924206 0.86 C3AR1 (0.34) NPY4RNPY1RNPY2RNPY5RITGB3
SCHEMBL2347308 0.85 ITGB3 (0.36) NPY4RNPY1RNPY2RNPY5RITGB3
SCHEMBL23296534 0.84 C3AR1 (0.35) NPY4RNPY1RNPY2RNPY5RITGB3
SCHEMBL2485111 0.84 C3AR1 (0.35) NPY4RNPY1RNPY2RNPY5RITGB3
SCHEMBL61231 0.83 FOLH1 (0.39) NPY4RNPY1RNPY2RNPY5RITGB3
SCHEMBL1263209 0.83 FOLH1 (0.39) NPY4RNPY1RNPY2RNPY5RITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5260373-A Immobilized immunoglobulin-binding proteins REPLIGEN CORPORATION (US) 1993-11-09 — — US claimed
US-5089605-A For purification of monoclonal antibodies REPLIGEN CORPORATION (US) 1992-02-18 — — US claimed
EP-0282308-A2 Immobilized immunoglobulin-binding proteins REPLIGEN CORPORATION (US) 1988-09-14 — — EP claimed
CN-102256936-B Arginine derivative and cosmetic comprising same NOF CORP 2014-06-18 — — CN disclosed
EP-2377848-B1 ARGININE DERIVATIVE AND COSMETIC COMPRISING SAME NOF CORP (JP) 2013-10-02 — — EP disclosed
US-8518994-B2 Arginine derivative and cosmetic containing the same NOF CORPORATION (JP) 2013-08-27 — — US disclosed
CN-102256936-A Arginine derivative and cosmetic comprising same NOF CORP 2011-11-23 — — CN disclosed
EP-2377848-A1 ARGININE DERIVATIVE AND COSMETIC COMPRISING SAME NOF Corporation (JP) 2011-10-19 — — EP disclosed
US-20110245344-A1 ARGININE DERIVATIVE AND COSMETIC CONTAINING THE SAME NOF CORPORATION (JP) 2011-10-06 — — US disclosed
US-5260373-A Immobilized immunoglobulin-binding proteins REPLIGEN CORPORATION (US) 1993-11-09 — — US disclosed
US-5089605-A For purification of monoclonal antibodies REPLIGEN CORPORATION (US) 1992-02-18 — — US disclosed
EP-0282308-A2 Immobilized immunoglobulin-binding proteins REPLIGEN CORPORATION (US) 1988-09-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245344-A1 ARGININE DERIVATIVE AND COSMETIC CONTAINING THE SAME ARG1, ARG2, ARGLU1 NPY4R 1138/4885NPY1R 284/4885NPY2R 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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