SCHEMBL24810938

SCHEMBL24810938

c1ccc(-c2cc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)nc(-c3c4ccccc4cc4ccccc34)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.46
▸ L3MBTL1 Q9Y468 4/20 0.46
▸ ATM Q13315 1/20 0.46
▸ KMT2A Q03164 8/20 0.40
▸ MEN1 O00255 6/20 0.40
▸ ALDH1A1 P00352 6/20 0.40
▸ HPGD P15428 6/20 0.40
▸ MAPT P10636 6/20 0.40
▸ NTSR1 P30989 1/20 0.40
▸ ADORA3 P0DMS8 1/20 0.37
▸ TDP1 Q9NUW8 2/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ CYP1A1 P04798 1/20 0.37
▸ CYP1B1 Q16678 1/20 0.37
▸ ADORA2A P29274 1/20 0.37
▸ ADORA1 P30542 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ HDAC4 P56524 1/20 0.36
▸ ALOX5 P09917 2/20 0.36
▸ ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21973998 0.95 L3MBTL1 (0.41) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL24812015 0.92 KMT2A (0.44) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL24812014 0.92 KMT2A (0.44) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL14416346 0.91 KMT2A (0.43) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL13233275 0.90 L3MBTL1 (0.41) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL24812018 0.90 KDM4E (0.47) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL17853574 0.90 DHODH (0.40) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL13233257 0.89 KDM4E (0.42) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL20161058 0.89 KDM4E (0.49) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL17853572 0.89 DHODH (0.41) KDM4EL3MBTL1ATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074311-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-02-29 — — US disclosed
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 KDM4E 3416/4885L3MBTL1 1876/4885ATM 3436/4885
US-20240074311-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE RPS12, TCF12, RRP12 KDM4E 2161/4885L3MBTL1 785/4885ATM 3325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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