Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24811374 | 0.88 | LMNA (0.41) | LMNAMEN1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL24477430 | 0.82 | FAAH (0.53) | DNM1MEN1FAAHMAPK1KMT2A | |
| SCHEMBL23419984 | 0.81 | FAAH (0.50) | DNM1MEN1FAAHMAPK1KMT2A | |
| SCHEMBL8170991 | 0.79 | DNM1 (0.48) | LMNADNM1 | |
| SCHEMBL9883738 | 0.77 | LMNA (0.43) | LMNAMEN1KMT2APDE3A | |
| SCHEMBL27010002 | 0.77 | PAOX (0.41) | LMNACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19090737 | 0.76 | — | — | |
| SCHEMBL14336264 | 0.74 | MCL1 (0.34) | LMNACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5508427 | 0.73 | TDP1 (0.36) | CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL23324950 | 0.73 | CHRNB2 (0.38) | LMNACHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |