Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 5/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25792485 | 0.94 | CASP2 (0.41) | CASP2FAAHNAAADNM1HDAC3 | |
| SCHEMBL19880193 | 0.92 | FAAH (0.44) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL29300290 | 0.85 | CASP2 (0.65) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL29302109 | 0.85 | CASP2 (0.65) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL25793454 | 0.84 | CASP2 (0.44) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL22008734 | 0.83 | CASP2 (0.52) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL19350634 | 0.83 | ALDH1A1 (0.47) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL21872513 | 0.83 | FAAH (0.57) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL25793668 | 0.83 | CASP2 (0.47) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL22302217 | 0.82 | MEN1 (0.44) | CASP2FAAHNAAAEPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |