Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25793462 | 0.98 | CASP2 (0.42) | CASP2FAAHNAAADNM1LPAR1 | |
| SCHEMBL25793564 | 0.90 | ALDH1A1 (0.42) | CASP2FAAHNAAADNM1LPAR1 | |
| SCHEMBL19880188 | 0.88 | CASP2 (0.52) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL25793510 | 0.88 | CASP2 (0.55) | CASP2FAAHNAAADNM1LPAR1 | |
| SCHEMBL19350634 | 0.86 | ALDH1A1 (0.47) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL29300290 | 0.85 | CASP2 (0.65) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL22013997 | 0.85 | NAAA (0.51) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL29302109 | 0.85 | CASP2 (0.65) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL24812433 | 0.84 | CASP2 (0.46) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL23320102 | 0.83 | NAMPT (0.47) | CASP2FAAHNAAADNM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |