Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 4/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909192 | 0.90 | ABL1 (0.35) | AKT1ABL1BCRPTGS2TSHR | |
| SCHEMBL23577305 | 0.90 | ABL1 (0.35) | AKT1ABL1BCRPTGS2TSHR | |
| SCHEMBL24813566 | 0.86 | TUBB4A (0.35) | ABL1BCR | |
| SCHEMBL24814803 | 0.85 | ACHE (0.34) | ABL1BCR | |
| SCHEMBL24813187 | 0.85 | AKT1 (0.34) | AKT1LRRK2 | |
| SCHEMBL24807050 | 0.85 | ABL1 (0.33) | AKT1ABL1BCRPTGS2TSHR | |
| SCHEMBL24813110 | 0.84 | HRH4 (0.32) | AKT1ABL1BCR | |
| SCHEMBL30047252 | 0.84 | HRH4 (0.32) | AKT1ABL1BCR | |
| SCHEMBL24816016 | 0.83 | DHODH (0.36) | — | |
| SCHEMBL29162213 | 0.81 | AKT1 (0.32) | AKT1ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359415-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117355531-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-05 | — | — | CN | disclosed |
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |