SCHEMBL24813358

SCHEMBL24813358

Pc1ccc2c(c1)oc1ccc(-c3ccc(-c4ccc(-c5cc(-c6ccc(-c7cccc8ccccc78)cc6)nc(-c6ccccc6)n5)cc4)cc3)cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
MAPT P10636 6/20 0.41
HPGD P15428 6/20 0.41
KDM4E B2RXH2 5/20 0.41
MAPK1 P28482 3/20 0.41
HSD17B10 Q99714 3/20 0.41
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TP53 P04637 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ENPP1 P22413 2/20 0.39
ENPP3 O14638 1/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15501305 0.91 ENPP3 (0.43) ALDH1A1MAPTHPGDKDM4EMAPK1
SCHEMBL15501313 0.91 ENPP3 (0.43) ALDH1A1MAPTHPGDKDM4EMAPK1
SCHEMBL17899247 0.89 ENPP3 (0.41) ALDH1A1MAPTHPGDKDM4EMAPK1
SCHEMBL15501396 0.89 ENPP3 (0.43) ALDH1A1MAPTHPGDKDM4EMAPK1
SCHEMBL15501399 0.88 ENPP3 (0.38) ALDH1A1MAPTHPGDKDM4EMAPK1
SCHEMBL17899228 0.87 ENPP3 (0.41) ALDH1A1MAPTHPGDKDM4EMAPK1
SCHEMBL25664682 0.87 ALDH1A1 (0.43) ALDH1A1MAPTHPGDKDM4EMAPK1
SCHEMBL19397395 0.86 ENPP1 (0.45) ALDH1A1MAPTHPGDKDM4EMAPK1
SCHEMBL15501753 0.85 ALDH1A1 (0.46) ALDH1A1MAPTHPGDKDM4EMAPK1
SCHEMBL17899241 0.84 ALDH1A1 (0.41) ALDH1A1MAPTHPGDKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 ALDH1A1 196/4885MAPT 1926/4885HPGD 4077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.