Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 5/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026646 | 0.84 | CASP6 (0.41) | IDO1TYMPCASP6HTTLMNA | |
| SCHEMBL7027217 | 0.84 | HTT (0.42) | ADRA2ACLCN2IDO1TYMPHTT | |
| SCHEMBL7034110 | 0.78 | IDH1 (0.35) | ADRA2ACLCN2IDO1TYMPHTT | |
| SCHEMBL3424330 | 0.75 | ADRA2A (0.44) | ADRA2ACLCN2ERCC1ERCC4DAO | |
| SCHEMBL25329522 | 0.75 | NQO2 (0.46) | CASP6HTTLMNAALDH1A1MAPT | |
| SCHEMBL7031565 | 0.70 | CAPN1 (0.40) | IDO1TYMPHTTPTK2BGDA | |
| SCHEMBL24815911 | 0.70 | DAO (0.46) | IDO1TYMPHTTLMNAALDH1A1 | |
| SCHEMBL22866846 | 0.70 | IDH1 (0.35) | IDO1TYMPHTTLMNAALDH1A1 | |
| SCHEMBL29561245 | 0.70 | IDH1 (0.35) | IDO1TYMPHTTLMNAALDH1A1 | |
| SCHEMBL7028889 | 0.69 | ALDH1A1 (0.38) | IDO1TYMPHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |