Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 8/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2110140 | 1.00 | KMT2A (0.39) | KMT2AMEN1MAPK1ITGB3ITGA2B | |
| SCHEMBL27218038 | 1.00 | KMT2A (0.39) | KMT2AMEN1MAPK1ITGB3ITGA2B | |
| SCHEMBL2549745 | 1.00 | KMT2A (0.39) | KMT2AMEN1MAPK1ITGB3ITGA2B | |
| SCHEMBL27218008 | 1.00 | KMT2A (0.39) | KMT2AMEN1MAPK1ITGB3ITGA2B | |
| SCHEMBL8271718 | 1.00 | KMT2A (0.39) | KMT2AMEN1MAPK1ITGB3ITGA2B | |
| SCHEMBL12852123 | 0.90 | DPP4 (0.40) | KMT2AMEN1MAPK1ITGB3ITGA2B | |
| SCHEMBL21157400 | 0.89 | ALDH1A1 (0.45) | KMT2AMEN1MAPK1ITGB3ITGA2B | |
| SCHEMBL8324848 | 0.88 | DPP4 (0.35) | KMT2AMEN1MAPK1ITGB3ITGA2B | |
| SCHEMBL12969913 | 0.86 | MEN1 (0.37) | KMT2AMEN1MAPK1ITGB3ITGA2B | |
| SCHEMBL8299304 | 0.86 | KMT2A (0.48) | KMT2AMEN1MAPK1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411362-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | K-GEN THERAPEUTICS, INC. | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411362-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | PRKCA, PRKCH, PRKCB | KMT2A 2943/4885MEN1 3968/4885MAPK1 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.