Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 6/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577188 | 0.86 | BCHE (0.40) | DHODHBCHEACHEGRIN1GRIN2A | |
| SCHEMBL29909143 | 0.86 | BCHE (0.40) | DHODHBCHEACHEGRIN1GRIN2A | |
| SCHEMBL24816016 | 0.85 | DHODH (0.36) | MAPK1KDM4EDHODHIDO1TDO2 | |
| SCHEMBL29909030 | 0.85 | KDM4E (0.33) | MAPK1LMNAHPGDKDM4ETSHR | |
| SCHEMBL24813187 | 0.84 | AKT1 (0.34) | — | |
| SCHEMBL29909109 | 0.83 | ACHE (0.34) | MAPK1LMNAHPGDKDM4ETSHR | |
| SCHEMBL23576881 | 0.83 | ACHE (0.34) | MAPK1LMNAHPGDKDM4ETSHR | |
| SCHEMBL24806346 | 0.74 | MAP4K1 (0.35) | — | |
| SCHEMBL30047169 | 0.73 | DHODH (0.32) | HPGDKDM4EDHODHSMN1; SMN2 | |
| SCHEMBL24806347 | 0.72 | ABL1 (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |