Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 6/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909344 | 0.85 | EGFR (0.36) | DHODHHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL23577369 | 0.85 | EGFR (0.36) | DHODHHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL24816017 | 0.85 | MAPK1 (0.36) | KDM4ELMNAHPGDTSHRMAPK1 | |
| SCHEMBL29909143 | 0.82 | BCHE (0.40) | DHODHTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23577188 | 0.82 | BCHE (0.40) | DHODHTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23601370 | 0.76 | HTR6 (0.33) | KDM4ELMNAHPGDMAPK1HTR6 | |
| SCHEMBL29909214 | 0.74 | MAPT (0.33) | HTR6GAAMAPT | |
| SCHEMBL23577938 | 0.74 | MAPT (0.33) | HTR6GAAMAPT | |
| SCHEMBL23576677 | 0.72 | PIK3CA (0.32) | — | |
| SCHEMBL29909207 | 0.72 | PIK3CA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |