Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.40 |
| ▸ | DHODH | Q02127 | 7/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.37 |
| ▸ | TUBB | P07437 | 4/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577188 | 1.00 | BCHE (0.40) | BCHEACHEGRIN1GRIN2ADHODH | |
| SCHEMBL24816017 | 0.86 | MAPK1 (0.36) | BCHEACHEGRIN1GRIN2ADHODH | |
| SCHEMBL29909744 | 0.84 | TUBB4A (0.44) | BCHEACHEGRIN1GRIN2ADHODH | |
| SCHEMBL23601562 | 0.84 | TUBB4A (0.44) | BCHEACHEGRIN1GRIN2ADHODH | |
| SCHEMBL30146546 | 0.84 | RET (0.32) | DHODHTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29141401 | 0.84 | RET (0.32) | DHODHTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29909030 | 0.82 | KDM4E (0.33) | DHODHTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL24813570 | 0.82 | ACHE (0.33) | ACHE | |
| SCHEMBL30047978 | 0.82 | ACHE (0.33) | ACHE | |
| SCHEMBL24813174 | 0.81 | ACHE (0.41) | ACHETUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |