Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481898 | 1.00 | ALDH1A1 (0.54) | ALDH1A1NPSR1KMT2AL3MBTL1GAA | |
| SCHEMBL5604107 | 0.78 | HTR3E (0.41) | ALDH1A1GAAMAPTHTR3ESLC22A2 | |
| SCHEMBL5604111 | 0.78 | HTR3E (0.41) | ALDH1A1GAAMAPTHTR3ESLC22A2 | |
| SCHEMBL11836951 | 0.77 | SIGMAR1 (0.53) | ALDH1A1L3MBTL1HPGDSIGMAR1PLAU | |
| SCHEMBL11836941 | 0.77 | SIGMAR1 (0.53) | ALDH1A1L3MBTL1HPGDSIGMAR1PLAU | |
| SCHEMBL109210 | 0.77 | HTR3E (0.54) | ALDH1A1NPSR1KMT2AMEN1MAPT | |
| SCHEMBL6049836 | 0.77 | HTR3E (0.54) | ALDH1A1NPSR1KMT2AMEN1MAPT | |
| Bromide SCHEMBL31532276 | 0.76 | NOS1 (0.54) | ALDH1A1NPSR1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL3143830 | 0.76 | HTR3E (0.52) | ALDH1A1NPSR1KMT2AMEN1SIGMAR1 | |
| SCHEMBL10661170 | 0.74 | POLB (0.52) | ALDH1A1NPSR1KMT2AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376074-A1 | METHOD FOR IMPROVED BIOACTIVATION OF MEDICATIONS | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co. KG (DE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010078867-A1 | METHOD FOR IMPROVED BIOACTIVATION OF MEDICATIONS | CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) | 2010-07-15 | — | — | WO | disclosed |