⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833142 | 0.95 | LMNA (0.30) | — | |
| SCHEMBL23374694 | 0.93 | LMNA (0.33) | — | |
| SCHEMBL27281329 | 0.87 | TSHR (0.41) | — | |
| SCHEMBL22151723 | 0.81 | — | — | |
| SCHEMBL13660263 | 0.77 | TSHR (0.44) | — | |
| SCHEMBL24818587 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL24820169 | 0.76 | SLC6A4 (0.36) | — | |
| SCHEMBL22519401 | 0.76 | PDCD1 (0.31) | — | |
| SCHEMBL4600596 | 0.76 | CHRNB2 (0.31) | — | |
| SCHEMBL23732171 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725010-B2 | Polyheterocyclic compounds as METTL3 inhibitors | STORM THERAPEUTICS LIMITED (GB) | 2023-08-15 | — | — | US | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |