Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | CBLB | Q13191 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820412 | 1.00 | CNR2 (0.44) | CNR2GRM2KCNH2CNR1PDE5A | |
| SCHEMBL24820421 | 1.00 | CNR2 (0.44) | CNR2GRM2KCNH2CNR1PDE5A | |
| SCHEMBL24820420 | 0.82 | CNR2 (0.44) | CNR2CBLB | |
| SCHEMBL24820408 | 0.82 | CNR2 (0.44) | CNR2CBLB | |
| SCHEMBL24820406 | 0.82 | CNR2 (0.44) | CNR2CBLB | |
| SCHEMBL24820334 | 0.81 | SIGMAR1 (0.42) | CNR2KCNH2 | |
| SCHEMBL24820342 | 0.81 | ALDH1A1 (0.44) | CNR2PDE5APDE11APDE10APIK3CD | |
| SCHEMBL24820338 | 0.81 | ALDH1A1 (0.44) | CNR2PDE5APDE11APDE10APIK3CD | |
| SCHEMBL24820340 | 0.81 | ALDH1A1 (0.44) | CNR2PDE5APDE11APDE10APIK3CD | |
| SCHEMBL24820357 | 0.80 | CNR2 (0.41) | CNR2GRM2KCNH2CNR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |