Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820407 | 0.77 | RXRA (0.32) | LMNA | |
| SCHEMBL24821729 | 0.74 | TDP1 (0.47) | POLBKDM4EMAPTNPC1RAB9A | |
| SCHEMBL3894242 | 0.72 | HPGDS (0.50) | HPGDSRPS6KA3RPS6KA2KDM4EMAPT | |
| SCHEMBL11499102 | 0.70 | HPGDS (0.54) | HPGDSRPS6KA3RPS6KA2POLBKDM4E | |
| SCHEMBL24820335 | 0.70 | HPGD (0.43) | POLBKDM4ELMNAMEN1NPC1 | |
| SCHEMBL3896671 | 0.69 | HPGDS (0.49) | HPGDSRPS6KA3RPS6KA2POLBKDM4E | |
| SCHEMBL24820414 | 0.66 | ACACB (0.45) | MEN1KMT2A | |
| SCHEMBL16789782 | 0.66 | MAPT (0.41) | POLBKDM4EMAPT | |
| SCHEMBL24820416 | 0.65 | HDAC4 (0.44) | NPC1RAB9AKMT2A | |
| SCHEMBL24820405 | 0.65 | HDAC4 (0.44) | NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |