Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.54 |
| ▸ | STAMBP | O95630 | 9/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 9/20 | 0.45 |
| ▸ | COPS5 | Q92905 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871494 | 0.77 | PSMD14 (0.69) | HPGDSSTAMBPPSMD14COPS5MAPT | |
| SCHEMBL28235432 | 0.74 | PSMD14 (0.60) | HPGDSSTAMBPPSMD14COPS5 | |
| SCHEMBL11375854 | 0.74 | GSK3A (0.37) | HPGDSKDM4EPOLBMAPT | |
| SCHEMBL7451848 | 0.73 | PSMD14 (0.61) | HPGDSSTAMBPPSMD14COPS5 | |
| SCHEMBL6084771 | 0.72 | TAS1R3 (0.57) | HPGDS | |
| SCHEMBL6084781 | 0.72 | TAS1R3 (0.57) | HPGDS | |
| SCHEMBL3894242 | 0.71 | HPGDS (0.50) | HPGDSKDM4ERPS6KA3RPS6KA2MAPT | |
| SCHEMBL10941294 | 0.71 | TYK2 (0.35) | HPGDSKDM4EMAPT | |
| SCHEMBL24820402 | 0.70 | HPGDS (0.43) | HPGDSKDM4EPOLBRPS6KA3RPS6KA2 | |
| SCHEMBL4158191 | 0.70 | ALDH1A1 (0.44) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040573-A2 | 2-Substituted-4-hydroxy-3-quinolinecarboxylic acids, their preparation, their use as medicaments, compositions containing them and intermediates | ROUSSEL-UCLAF (FR) | 1981-11-25 | — | — | EP | disclosed |