Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 6/20 | 0.33 |
| ▸ | CBLB | Q13191 | 5/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820485 | 1.00 | CETP (0.33) | CETPCBLBS1PR1S1PR3IDO1 | |
| SCHEMBL24821968 | 0.91 | CYP11B2 (0.33) | CETPCBLBIDO1CYP11B2KCNH2 | |
| SCHEMBL30153034 | 0.91 | CYP11B2 (0.33) | CETPCBLBIDO1CYP11B2KCNH2 | |
| SCHEMBL30153007 | 0.90 | CBLB (0.36) | CETPCBLBS1PR1IDO1CYP11B2 | |
| SCHEMBL24821927 | 0.90 | CBLB (0.36) | CETPCBLBS1PR1IDO1CYP11B2 | |
| SCHEMBL30792010 | 0.90 | CBLB (0.36) | CETPCBLBS1PR1IDO1CYP11B2 | |
| SCHEMBL24818673 | 0.88 | HPGD (0.37) | CETPCBLBS1PR1 | |
| SCHEMBL30792096 | 0.88 | HPGD (0.37) | CETPCBLBS1PR1 | |
| SCHEMBL30153040 | 0.88 | HPGD (0.37) | CETPCBLBS1PR1 | |
| SCHEMBL24818992 | 0.86 | HDAC6 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |