Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153034 | 1.00 | CYP11B2 (0.33) | CYP11B2IDO1CYP11B1MAP3K5HDAC3 | |
| SCHEMBL24820485 | 0.91 | CETP (0.33) | CYP11B2IDO1CYP11B1CBLBKCNH2 | |
| SCHEMBL30153198 | 0.91 | CETP (0.33) | CYP11B2IDO1CYP11B1CBLBKCNH2 | |
| SCHEMBL30792046 | 0.89 | MAP3K5 (0.34) | CYP11B2IDO1CYP11B1MAP3K5HPGD | |
| SCHEMBL24820582 | 0.89 | MAP3K5 (0.34) | CYP11B2IDO1CYP11B1MAP3K5HPGD | |
| SCHEMBL30152957 | 0.89 | MAP3K5 (0.34) | CYP11B2IDO1CYP11B1MAP3K5HPGD | |
| SCHEMBL24818992 | 0.89 | HDAC6 (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30153052 | 0.89 | HDAC6 (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL24821906 | 0.88 | HPGD (0.39) | HPGDMAPTESR2KDM4ENPC1 | |
| SCHEMBL30153089 | 0.88 | HPGD (0.39) | HPGDMAPTESR2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |