Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391624 | 1.00 | PDE10A (0.32) | PDE10ACSNK1EPDE2APDK1PDK2 | |
| SCHEMBL23625903 | 0.79 | RAB9A (0.37) | — | |
| SCHEMBL30952889 | 0.79 | RAB9A (0.37) | — | |
| SCHEMBL31391633 | 0.79 | — | — | |
| SCHEMBL24823316 | 0.79 | — | — | |
| SCHEMBL24823318 | 0.72 | DYRK1A (0.37) | — | |
| SCHEMBL30310926 | 0.72 | DYRK1A (0.37) | — | |
| SCHEMBL24823317 | 0.72 | DYRK1A (0.37) | — | |
| SCHEMBL30310938 | 0.72 | DYRK1A (0.37) | — | |
| SCHEMBL24823325 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022267930-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2022-12-29 | — | — | WO | disclosed |