SCHEMBL2482486

SCHEMBL2482486

CCCCC1CCCNC(=O)C1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.47
CCR2 P41597 5/20 0.39
NAAA Q02083 1/20 0.35
MMP1 P03956 1/20 0.35
MMP3 P08254 1/20 0.35
MMP9 P14780 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTT P42858 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
SIRT3 Q9NTG7 1/20 0.34
ALDH1A1 P00352 3/20 0.33
OR51E2 Q9H255 1/20 0.33
TLR4 O00206 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9766490 0.93 CYP1A2 (0.49) CYP1A2CCR2HTTALDH1A1L3MBTL1
SCHEMBL26718370 0.89 CYP1A2 (0.46) CYP1A2CCR2NAAATDP1HTT
SCHEMBL2482364 0.89 CHRNA7 (0.38) CYP1A2CCR2HTTALDH1A1OR51E2
SCHEMBL1567651 0.84 CYP1A2 (0.53) CYP1A2CCR2NAAAALDH1A1L3MBTL1
SCHEMBL27924745 0.83 OR51E2 (0.33) CYP1A2OR51E2FKBP5CRBN
SCHEMBL28731850 0.83 SIGMAR1 (0.40) CYP1A2TDP1OR51E2FKBP5CRBN
SCHEMBL7626924 0.83 CYP1A2 (0.51) CYP1A2CCR2NAAAALDH1A1L3MBTL1
SCHEMBL7624660 0.83 CYP1A2 (0.51) CYP1A2CCR2NAAAALDH1A1L3MBTL1
SCHEMBL2526110 0.82 HTT (0.41) CCR2HTTALDH1A1OR51E2L3MBTL1
SCHEMBL5014640 0.80 OR51E2 (0.37) OR51E2FKBP5CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080182773-A1 Thickeners Based on Polymers Comprising Amine Groups BASF AKTIENGESELLSCHAFT (DE) 2008-07-31 US claimed
EP-1863574-A1 THICKENER BASED ON AMINE GROUP-CONTAINING POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2007-12-12 EP claimed
WO-2006100299-A1 THICKENER BASED ON AMINE GROUP-CONTAINING POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 WO claimed
CN-120157874-A High-elasticity light nylon elastomer and hydrolytic polymerization preparation method thereof 浙江恒逸石化研究院有限公司 2025-06-17 CN disclosed
EP-2170964-B1 HIGH-CATION COPOLYMERS BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS BASF SE (DE) 2017-02-22 EP disclosed
WO-2017012963-A1 POLYMERIZABLE FATTY ACID-DERIVATIVE-MONOMERS WITH TERMINAL OLEFINIC DOUBLE BONDS, POLYMERS CONTAINING SAME MONOMERS, PRODUCTION AND USE THEREOF BASF SE (DE) 2017-01-26 WO disclosed
US-8623343-B2 Highly cationic copolymers based on quaternized nitrogen-containing monomers BASF SE (DE) 2014-01-07 US disclosed
US-20130108959-A1 USE OF A COMPOSITION COMPRISING VINYL MONOMER-COMPRISING POLYMER, SOLVENT AND AT LEAST ONE HALOGEN-FREE BIOCIDE BASF SE (DE) 2013-05-02 US disclosed
US-20120118446-A1 AQUEOUS METAL QUENCHING MEDIUM BASF SE (DE) 2012-05-17 US disclosed
EP-2376550-A1 MODIFIED POLYVINYLLACTAMS BASF SE (DE) 2011-10-19 EP disclosed
US-20110248428-A1 MODIFIED POLYVINYLLACTAMS BASF SE (DE) 2011-10-13 US disclosed
WO-2006100299-A1 THICKENER BASED ON AMINE GROUP-CONTAINING POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 WO disclosed
EP-1240139-B1 METHOD FOR PRODUCING N-ALKENYL AMIDES BASF AG (DE) 2005-11-09 EP disclosed
US-6794546-B2 REACTION OF CORRESPONDING OH, SH OR NH COMPOUND WITH AN ACETYLENE IN LIQUID PHASE IN PRESENCE OF BASIC ALKALI OR ALKALINE EARTH METAL COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2004-09-21 US disclosed
EP-1240140-B1 METHOD FOR THE PRODUCTION OF N-ALKENYL AMIDES BASF AG (DE) 2004-03-17 EP disclosed
US-6673920-B2 REACTING AMIDES WITH ACETYLENES IN THE LIQUID PHASE IN THE PRESENCE OF BASIC ALKALI METAL COMPOUNDS AND OF A COCATALYST, WHICH COMPRISES USING AS THE COCATALYST DIOLS TO PREPARE N-ALKENYL-AMIDE BASF AKTIENGESELLSCHAFT (DE) 2004-01-06 US disclosed
US-6624303-B2 By reacting the corresponding NH-amides with acetylenes in the liquid phase using a basic alkali metal compound as catalyst and as cocatalyst (di- or tri-)1,4-butanediol mono- and diethers; N-vinyl-2-pyrrolidone from pyrrolidone BASF AKTIENGESELLSCHAFT (DE) 2003-09-23 US disclosed
US-20030105354-A1 Reaction of corresponding OH, SH or NH compound with an acetylene in liquid phase in presence of basic alkali or alkaline earth metal compounds BASF AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
US-20030036659-A1 Method for the production of n-alkenyl amides BASF AKTIENGESELLSCHAFT (DE) 2003-02-20 US disclosed
US-20030028035-A1 Method for producing n-alkenyl amides BASF AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036659-A1 Method for the production of n-alkenyl amides NAT1, SAT1, AGPAT2 CYP1A2 184/4885CCR2 1245/4885NAAA 7/4885
US-20030028035-A1 Method for producing n-alkenyl amides NAT1, H1-2, H1-0 CYP1A2 435/4885CCR2 377/4885NAAA 48/4885
US-20030105354-A1 Reaction of corresponding OH, SH or NH compound with an acetylene in liquid phase in presence of basic alkali or alkaline earth metal compounds H1-0, HAT1, H1-3 CYP1A2 1740/4885CCR2 4858/4885NAAA 55/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.