Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014640 | 0.84 | OR51E2 (0.37) | OR51E2FKBP5CRBN | |
| SCHEMBL27924745 | 0.83 | OR51E2 (0.33) | OR51E2FKBP5CRBNCYP1A2 | |
| SCHEMBL2482486 | 0.83 | CYP1A2 (0.47) | TDP1OR51E2FKBP5CRBNCYP1A2 | |
| SCHEMBL9766490 | 0.80 | CYP1A2 (0.49) | CYP1A2 | |
| SCHEMBL2482364 | 0.79 | CHRNA7 (0.38) | OR51E2FKBP5CRBNCYP1A2 | |
| SCHEMBL21494787 | 0.78 | OPRL1 (0.34) | — | |
| SCHEMBL2526110 | 0.74 | HTT (0.41) | OR51E2FKBP5CRBN | |
| SCHEMBL6969263 | 0.73 | NOS3 (0.38) | OR51E2FKBP5CRBN | |
| SCHEMBL5015068 | 0.72 | OPRL1 (0.35) | OR51E2 | |
| SCHEMBL26718370 | 0.71 | CYP1A2 (0.46) | TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478540-B | DBU synthesis method | 玉门千华制药有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-114478540-A | DBU synthesis method | 玉门千华制药有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114478540-B | DBU synthesis method | 玉门千华制药有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-114478540-A | DBU synthesis method | 玉门千华制药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478540-A | DBU synthesis method | 玉门千华制药有限公司 | 2022-05-13 | — | — | CN | disclosed |