Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | TPO | P07202 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184112 | 1.00 | IDO1 (0.42) | IDO1KLF10PNMTTAAR1MPO | |
| Hydrochloric Acid SCHEMBL29187473 | 0.98 | IDO1 (0.45) | IDO1KLF10PNMTTAAR1MPO | |
| SCHEMBL31085526 | 0.88 | KLF10 (0.44) | IDO1KLF10KDM4EALDH1A1HPGD | |
| SCHEMBL1014987 | 0.88 | KLF10 (0.44) | IDO1KLF10KDM4EALDH1A1HPGD | |
| SCHEMBL4624085 | 0.81 | KLF10 (0.47) | KLF10ALDH1A1HPGDHSD17B10CYP2D6 | |
| SCHEMBL10233691 | 0.81 | ESR1 (0.43) | IDO1KLF10CYP3A4CYP2D6FFAR4 | |
| SCHEMBL1261721 | 0.78 | ALDH1A1 (0.46) | IDO1KLF10KDM4EALDH1A1HPGD | |
| SCHEMBL3174968 | 0.78 | MEN1 (0.44) | IDO1KLF10PNMTTAAR1KDM4E | |
| SCHEMBL5102965 | 0.78 | ALDH1A1 (0.50) | IDO1KLF10KDM4EALDH1A1HPGD | |
| SCHEMBL16956734 | 0.78 | VDR (0.44) | IDO1KLF10CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836273-A | Methods for preparing CYP11A1 inhibitors and intermediates thereof | 奥仁公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2022269134-A1 | PROCESS FOR THE PREPARATION OF A CYP11A1 INHIBITOR AND INTERMEDIATES THEREOF | ORION CORPORATION (FI) | 2022-12-29 | — | — | WO | disclosed |