Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLF10 | Q13118 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014987 | 1.00 | KLF10 (0.44) | KLF10IDO1CYP3A4CYP2D6CES2 | |
| SCHEMBL24825592 | 0.88 | IDO1 (0.42) | KLF10IDO1CYP3A4CYP2D6CES2 | |
| SCHEMBL30184112 | 0.88 | IDO1 (0.42) | KLF10IDO1CYP3A4CYP2D6CES2 | |
| SCHEMBL10233691 | 0.88 | ESR1 (0.43) | KLF10IDO1CYP3A4CYP2D6CES2 | |
| Hydrochloric Acid SCHEMBL29187473 | 0.86 | IDO1 (0.45) | KLF10IDO1CYP3A4CYP2D6KDM4E | |
| SCHEMBL16956734 | 0.85 | VDR (0.44) | KLF10IDO1CYP3A4CYP2D6PDE2A | |
| SCHEMBL1993639 | 0.84 | CES2 (0.52) | IDO1CYP3A4CYP2D6CES2 | |
| SCHEMBL2161227 | 0.83 | ESR1 (0.45) | KLF10IDO1FFAR4 | |
| SCHEMBL561439 | 0.83 | KLF10 (0.66) | KLF10IDO1CYP2D6FFAR4SIRT2 | |
| SCHEMBL2000882 | 0.83 | CES2 (0.50) | KLF10IDO1CYP3A4CYP2D6CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4644384-A1 | CYP11A1 INHIBITOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Lichun Biotech Co., Ltd. (CN) | 2025-11-05 | — | — | EP | disclosed |
| CN-118307519-A | CYP11A1 inhibitor compound, preparation method and application thereof | 上海闻耐医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |