Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90257 | 0.85 | CA12 (0.40) | AAK1CA12CA14CA2TDP1 | |
| SCHEMBL18138208 | 0.77 | TDP1 (0.40) | AAK1CA12CA14CA2TDP1 | |
| SCHEMBL24826917 | 0.75 | AAK1 (0.37) | AAK1CA12CA14CA2TDP1 | |
| SCHEMBL25375682 | 0.72 | CTSK (0.38) | AAK1CA12CA14CA2TDP1 | |
| SCHEMBL25375678 | 0.72 | CTSK (0.38) | AAK1CA12CA14CA2TDP1 | |
| SCHEMBL7923566 | 0.71 | CA2 (0.42) | CA12CA14CA2TDP1CA1 | |
| SCHEMBL18961999 | 0.70 | GAA (0.38) | CYP1A2CYP2C9CYP2C19HTTKMT2A | |
| SCHEMBL31346359 | 0.68 | DGAT1 (0.45) | AAK1CA12CA14CA2TDP1 | |
| SCHEMBL22164468 | 0.68 | TDP1 (0.38) | AAK1CA12CA14CA2TDP1 | |
| SCHEMBL22164466 | 0.68 | TDP1 (0.38) | AAK1CA12CA14CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268913-A1 | NUCLEIC ACID CONTAINING NANOPARTICLES | BIO-TRIP B.V. (NL) | 2022-12-29 | — | — | WO | disclosed |