SCHEMBL2483045

SCHEMBL2483045

O=c1c(CO)c(CO)oc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.53
CYP3A4 P08684 3/20 0.53
ALDH1A1 P00352 2/20 0.53
KDM4E B2RXH2 2/20 0.53
GLA P06280 1/20 0.53
MAPT P10636 1/20 0.53
HPGD P15428 1/20 0.53
PGAM1 P18669 1/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAOB P27338 1/20 0.50
CYP2C9 P11712 6/20 0.45
MEN1 O00255 2/20 0.45
LMNA P02545 2/20 0.45
TP53 P04637 2/20 0.45
MAPK1 P28482 2/20 0.45
KMT2A Q03164 2/20 0.45
ABCB11 O95342 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18222929 0.82 CYP2C9 (0.47) MAOACYP3A4ALDH1A1KDM4EGLA
SCHEMBL19846946 0.78 KMT2A (0.64) MAOACYP3A4ALDH1A1KDM4EGLA
SCHEMBL13348986 0.76 ABCB1 (0.46) CYP3A4ALDH1A1MAPTHPGDHSD17B10
SCHEMBL14533465 0.75 CYP2C9 (0.55) MAOACYP3A4ALDH1A1KDM4EGLA
SCHEMBL311868 0.74 CYP3A4 (0.68) MAOACYP3A4ALDH1A1KDM4EMAPT
SCHEMBL1568301 0.74 NQO1 (0.66) CYP3A4ALDH1A1KDM4ECYP2C9MEN1
SCHEMBL33892 0.73 CYP3A4 (0.59) MAOACYP3A4ALDH1A1KDM4EGLA
SCHEMBL3456740 0.72 MAOA (0.42) MAOACYP3A4ALDH1A1KDM4EGLA
SCHEMBL27978165 0.72 MAOA (0.42) MAOACYP3A4ALDH1A1KDM4EGLA
SCHEMBL6854050 0.72 CYP2C19 (0.40) MAOACYP3A4ALDH1A1KDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117956977-A Cosmetic composition 布茨公司 2024-04-30 CN claimed
EP-4326892-A1 METHOD FOR SELECTING ECOBIOLOGICAL TOPICAL COMPOSITIONS AND INGREDIENTS CAPABLE OF RESTORING OR REINFORCING THE SKIN MICROBIOTA NAOS Institute of Life Science (FR) 2024-02-28 EP claimed
WO-2022223928-A1 METHOD FOR SELECTING ECOBIOLOGICAL TOPICAL COMPOSITIONS AND INGREDIENTS CAPABLE OF RESTORING OR REINFORCING THE SKIN MICROBIOTA NAOS INSTITUTE OF LIFE SCIENCE (FR) 2022-10-27 WO claimed
EP-3897867-A2 COSMETIC COMPOSITIONS Mary Kay, Inc. (US) 2021-10-27 EP claimed
CN-106659915-B Skin care compositions 博姿有限公司 2021-05-07 CN claimed
CN-112533493-A Enzyme molecules that mimic antioxidant activity 比奥尼克莱公司 2021-03-19 CN claimed
US-20200197472-A1 COSMETIC COMPOSITIONS MARY KAY INC. 2020-06-25 US claimed
WO-2020131477-A2 COSMETIC COMPOSITIONS MARY KAY INC. (US) 2020-06-25 WO claimed
EP-2706981-B1 COSMETIC COMPOSITIONS MARY KAY INC (US) 2019-09-04 EP claimed
EP-2788010-B1 SKIN CARE FORMULATION MARY KAY INC (US) 2018-10-24 EP claimed
CN-107961211-A Cosmetic composition 玫琳凯有限公司 2018-04-27 CN claimed
US-9526689-B2 Skin care formulation MARY KAY INC. (US) 2016-12-27 US claimed
US-9233062-B2 Cosmetic compositions MARY KAY INC. (US) 2016-01-12 US claimed
EP-2788010-A1 SKIN CARE FORMULATION Mary Kay, Inc. (US) 2014-10-15 EP claimed
EP-2706981-A2 COSMETIC COMPOSITIONS MARY KAY INC. (US) 2014-03-19 EP claimed
US-20130171283-A1 SKIN CARE FORMULATION MARY KAY INC. (US) 2013-07-04 US claimed
WO-2013086518-A1 SKIN CARE FORMULATION MARY KAY INC. (US) 2013-06-13 WO claimed
CN-103037838-A cosmetic composition MARY KAY INC 2013-04-10 CN claimed
WO-2012154949-A2 COSMETIC COMPOSITIONS MARY KAY INC. (US) 2012-11-15 WO claimed
US-20120288478-A1 COSMETIC COMPOSITIONS MARY KAY, INC. 2012-11-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200197472-A1 COSMETIC COMPOSITIONS GLA, GUSB, MMP2 MAOA 277/4885CYP3A4 3786/4885ALDH1A1 756/4885
US-20120288478-A1 COSMETIC COMPOSITIONS HEXA, GLA, HEXB MAOA 302/4885CYP3A4 3362/4885ALDH1A1 566/4885
US-20130171283-A1 SKIN CARE FORMULATION CUTA, TYR, RAD50 MAOA 765/4885CYP3A4 1799/4885ALDH1A1 3307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.