Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.58 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 5/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30078684 | 1.00 | ALDH1A1 (0.58) | ALDH1A1IMPDH2KDM4ESMN1; SMN2HTT | |
| SCHEMBL1828339 | 0.77 | ALDH1A1 (0.61) | ALDH1A1IMPDH2KDM4ESMN1; SMN2HTT | |
| SCHEMBL5545120 | 0.77 | ALDH1A1 (0.61) | ALDH1A1IMPDH2KDM4ESMN1; SMN2HTT | |
| SCHEMBL323912 | 0.75 | KMT2A (0.59) | ALDH1A1IMPDH2SMN1; SMN2HTTLMNA | |
| SCHEMBL30718496 | 0.75 | KMT2A (0.59) | ALDH1A1IMPDH2SMN1; SMN2HTTLMNA | |
| SCHEMBL9412272 | 0.74 | ALDH1A1 (0.78) | ALDH1A1IMPDH2KDM4ESMN1; SMN2HTT | |
| SCHEMBL21505492 | 0.74 | MEN1 (0.64) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL3831676 | 0.73 | ALDH1A1 (0.61) | ALDH1A1IMPDH2KDM4ESMN1; SMN2HTT | |
| SCHEMBL5503150 | 0.73 | ALDH1A1 (0.61) | ALDH1A1IMPDH2KDM4ESMN1; SMN2HTT | |
| SCHEMBL7202295 | 0.73 | ALDH1A1 (0.61) | ALDH1A1IMPDH2KDM4ESMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280638-A1 | VINYL THIANTHRENIUM COMPOUND, PROCESS FOR ITS PREPARATION AND ITS USE FOR TRANSFERRING A VINYL GROUP | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-01-12 | — | — | WO | disclosed |
| EP-4112600-A1 | VINYL THIANTHRENIUM COMPOUND, PROCESS FOR ITS PREPARATION AND ITS USE FOR TRANSFERRING A VINYL GROUP | Studiengesellschaft Kohle mbH (DE) | 2023-01-04 | — | — | EP | disclosed |