Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718496 | 1.00 | KMT2A (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| 3-Formylindole SCHEMBL1082058 | 0.86 | IMPDH2 (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL20931418 | 0.86 | KMT2A (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL31158212 | 0.85 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL27608925 | 0.84 | ALDH1A1 (0.63) | KMT2AALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL16344097 | 0.84 | KMT2A (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2189025 | 0.81 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL379309 | 0.81 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2187571 | 0.81 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30512327 | 0.81 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250364-B | Preparation method of polymeric material for dimethyl carbonate | 浙江蓝域智能科技有限公司 | 2020-12-04 | — | — | CN | claimed |
| US-12459893-B2 | Indole-ynone mediated benzoannulation process for the preparation of carbazoles, carbazomycin A, calothrixin B and staurosporinone | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2025-11-04 | — | — | US | disclosed |
| CN-116535386-B | Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof | 西南大学 | 2025-05-27 | — | — | CN | disclosed |
| CN-117624062-A | Barbiturates structure-containing compound and preparation method and application thereof | 武汉大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-117285511-A | Indole hybridized quinolone compound and preparation method and application thereof | 西南大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-116535386-A | Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof | 西南大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-115108959-B | Photobleachable visible light initiator containing benzylidene ketone structure, and preparation method and application thereof | 武汉大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-115108959-A | Photobleachable visible light initiator containing benzylidene ketone structure and preparation method and application thereof | 武汉大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-112921346-B | Electrochemical synthesis method of 3-formyl indole derivative | 浙江工业大学 | 2022-07-08 | — | — | CN | disclosed |
| US-20220169609-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES, CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-06-02 | — | — | US | disclosed |
| US-7622594-B2 | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622594-B2 | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| WO-2009135299-A1 | 3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2009-11-12 | — | — | WO | disclosed |
| EP-1893588-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2008-03-05 | — | — | EP | disclosed |
| US-20070060633-A1 | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-03-15 | — | — | US | disclosed |
| US-20070060633-A1 | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-03-15 | — | — | US | disclosed |
| WO-2006135826-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-21 | — | — | WO | disclosed |
| EP-1044214-A1 | METHOD FOR BINDING ALBUMIN AND MEANS TO BE USED IN THE METHOD | Amersham Pharmacia Biotech AB (SE) | 2000-10-18 | — | — | EP | disclosed |
| US-5994507-A | CONTACTING AQUEOUS LIQUID CONTAINING ALBUMIN WITH A COMPOUND CONTAINING THE SCAFFOLD--C(=O)-NH-C(=C-)-C(=O)- AND HAVING BEEN PRE-CHECKED TO BIND TO THE ALBUMIN; FOR REMOVAL OF ALBUMIN FROM A SOLUTION OR FOR PURIFICATION OF ALBUMIN | AMERSHAM PHARMACIA BIOTECH AB (SE) | 1999-11-30 | — | — | US | disclosed |
| WO-1999033860-A1 | METHOD FOR BINDING ALBUMIN AND MEANS TO BE USED IN THE METHOD | AMERSHAM PHARMACIA BIOTECH AB (SE) | 1999-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459893-B2 | Indole-ynone mediated benzoannulation process for the preparation of carbazoles, carbazomycin A, calothrixin B and staurosporinone | CYC1, CYCS, CANX | KMT2A 2835/4885MEN1 3856/4885ALDH1A1 4775/4885 |
| US-20220169609-A1 | INDOLE-YNONE MEDIATED BENZOANNULATION PROCESS FOR THE PREPARATION OF CARBAZOLES, CARBAZOMYCIN A, CALOTHRIXIN B AND STAUROSPORINONE | CYC1, CYCS, CANX | KMT2A 2835/4885MEN1 3856/4885ALDH1A1 4775/4885 |
| US-20070060633-A1 | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | NR3C1, MC2R, NR3C2 | KMT2A 3775/4885MEN1 1410/4885ALDH1A1 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.