Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18811640 | 0.91 | NPY5R (0.39) | SIRT2SIRT1OPRL1SIRT3 | |
| SCHEMBL19522921 | 0.90 | FAP (0.41) | SIRT2SIRT1OPRL1SIRT3SIRT5 | |
| SCHEMBL16904950 | 0.90 | FAP (0.41) | SIRT2SIRT1OPRL1SIRT3SIRT5 | |
| SCHEMBL19733545 | 0.90 | FAP (0.41) | SIRT2SIRT1OPRL1SIRT3SIRT5 | |
| SCHEMBL13477994 | 0.90 | FAP (0.41) | SIRT2SIRT1OPRL1SIRT3SIRT5 | |
| SCHEMBL18177084 | 0.90 | FAP (0.41) | SIRT2SIRT1OPRL1SIRT3SIRT5 | |
| SCHEMBL22969857 | 0.89 | NPY4R (0.41) | SIRT2SIRT1OPRL1ITGB1ITGA5 | |
| SCHEMBL22624856 | 0.89 | FAP (0.40) | SIRT2SIRT1OPRL1SIRT3SIRT5 | |
| SCHEMBL22970116 | 0.87 | MAP1LC3B (0.40) | SIRT2SIRT1OPRL1SIRT3SIRT5 | |
| SCHEMBL22969940 | 0.86 | OPRL1 (0.42) | SIRT2SIRT1OPRL1SIRT5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024052685-A1 | CYTOTOXIC IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY | MyricX Pharma Limited (GB) | 2024-03-14 | — | — | WO | disclosed |
| EP-3607996-B1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2023-01-04 | — | — | EP | disclosed |