SCHEMBL2483233

SCHEMBL2483233

CC(=O)SCC1OCCO1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACE P12821 3/20 0.35
CYP2C19 P33261 1/20 0.33
POLB P06746 1/20 0.32
BLM P54132 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2481861 0.77 CYP2C19 (0.40) CYP2C19POLBBLMATM
SCHEMBL31650790 0.76
SCHEMBL2480903 0.73 KMT2A (0.46) POLB
SCHEMBL1691075 0.71 KMT2A (0.41) POLB
SCHEMBL1691352 0.71 KMT2A (0.41) POLB
SCHEMBL2483886 0.71 KMT2A (0.41) POLB
SCHEMBL766758 0.71 PIK3CD (0.37) ACECYP2C19
SCHEMBL10917372 0.70 ALDH1A1 (0.35)
SCHEMBL13741476 0.69
SCHEMBL10636627 0.69 ACE (0.31) ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8513162-B2 Halogen-containing organosulfur compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-20 US disclosed
US-8513162-B2 Halogen-containing organosulfur compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-20 US disclosed
US-8513162-B2 Halogen-containing organosulfur compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-20 US disclosed
US-20110257226-A1 HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-20 US disclosed
US-20110257226-A1 HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-20 US disclosed
EP-2376450-A1 HALOGEN-CONTAINING ORGANOSULFUR COMPOUNDS AND USE THEREOF FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2011-10-19 EP disclosed
WO-2010074327-A1 HALOGEN-CONTAINING ORGANOSULFUR COMPOUNDS AND USE THEREOF FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-01 WO disclosed
EP-1524286-B1 Poly(benzodithiophenes) MERCK PATENT GMBH (DE) 2009-12-16 EP disclosed
US-7524922-B2 Poly(benzodithiophenes) MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2009-04-28 US disclosed
US-20050082525-A1 Poly(benzodithiophenes) Raynergy Tek Incorporation (TW) 2005-04-21 US disclosed
EP-1524286-A1 Poly(benzodithiophenes) MERCK PATENT GmbH (DE) 2005-04-20 EP disclosed
EP-0138538-B1 2-DIOXACYCLOALKYLTHIOPENEM DERIVATIVES PFIZER INC. (US) 1988-12-14 EP disclosed
US-4614737-A ANTIBIOTICS PFIZER INC. (US) 1986-09-30 US disclosed
EP-0138538-A1 2-Dioxacycloalkylthiopenem derivatives PFIZER INC. (US) 1985-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050082525-A1 Poly(benzodithiophenes) FHIT, GFPT1, RFT1 ACE 4319/4885CYP2C19 2226/4885POLB 4551/4885
US-20110257226-A1 HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF C1S, C5, L3MBTL3 ACE 2676/4885CYP2C19 2025/4885POLB 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.