Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24834482 | 0.88 | CYP2C19 (0.49) | ALOX15TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31325032 | 0.83 | TSHR (0.41) | ALOX15TSHRRAB9AAKR1B1 | |
| SCHEMBL25332425 | 0.82 | NLRP3 (0.40) | ALOX15TSHRCMA1RAB9A | |
| SCHEMBL24834532 | 0.82 | NLRP3 (0.45) | ALOX15RAB9A | |
| SCHEMBL24834837 | 0.81 | ALOX15 (0.60) | ALOX15TSHRCMA1MAPTPTGDR2 | |
| SCHEMBL31325030 | 0.81 | NLRP3 (0.49) | ALOX15TSHRMAPTAKR1B1 | |
| SCHEMBL24834535 | 0.81 | NLRP3 (0.47) | ALOX15TSHRAKR1B1 | |
| SCHEMBL24834513 | 0.78 | ALOX15 (0.56) | ALOX15TSHRCMA1MAPTPTGDR2 | |
| SCHEMBL24834578 | 0.78 | ALOX15 (0.56) | ALOX15TSHRCMA1MAPTPTGDR2 | |
| SCHEMBL30169728 | 0.78 | ALOX15 (0.56) | ALOX15TSHRCMA1MAPTPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023275230-A1 | 5-OXO-PYRIDO[2,3-D]PYRIDAZIN-6(5H)-YL ACETAMIDES | JANSSEN PHARMACEUTICA NV (BE) | 2023-01-05 | — | — | WO | disclosed |