Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24835175 | 0.86 | HDAC8 (0.43) | HDAC8HDAC6PTPN1L3MBTL1KDM4E | |
| SCHEMBL24835223 | 0.81 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1FDPS | |
| SCHEMBL24835222 | 0.80 | CYP4A11 (0.50) | L3MBTL1KDM4EALDH1A1MAPK1LMNA | |
| SCHEMBL8442436 | 0.73 | SCN9A (0.48) | HDAC8HDAC6PTPN1KDM4ESCN9A | |
| SCHEMBL8380879 | 0.72 | PTPN1 (0.40) | PTPN1KDM4EPPARAPLK1HDAC3 | |
| SCHEMBL9826682 | 0.71 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPK1LMNAMCHR1 | |
| SCHEMBL7973340 | 0.71 | PLK1 (0.61) | PTPN1KDM4ESCN9AALDH1A1PLK1 | |
| Hydrochloric Acid SCHEMBL8377317 | 0.71 | PTPN1 (0.39) | PTPN1KDM4EPPARAPLK1HDAC3 | |
| SCHEMBL10202053 | 0.70 | SCN9A (0.50) | HDAC8HDAC6PTPN1KDM4ESCN9A | |
| SCHEMBL4184807 | 0.69 | RARB (0.62) | PTPN1KDM4ESCN9AALDH1A1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |