SCHEMBL24835490

SCHEMBL24835490

CCn1ncc2nccnc2c1=O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
KMT2A Q03164 1/20 0.41
BRD4 O60885 1/20 0.34
BPTF Q12830 1/20 0.34
TBXAS1 P24557 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TOP2A P11388 1/20 0.32
TGFBR1 P36897 1/20 0.32
XDH P47989 1/20 0.31
KAT2B Q92831 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.30
POLB P06746 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19153135 0.76 KAT2B (0.38) GAABRD4BPTFALDH1A1KAT2B
SCHEMBL12844448 0.73 XDH (0.41) GAAKMT2ATGFBR1XDHHPGD
SCHEMBL18237768 0.71 BPTF (0.33) BPTFALDH1A1KAT2B
SCHEMBL22477679 0.69 TRPA1 (0.47) GAAKMT2AALDH1A1LMNAPOLB
SCHEMBL14038250 0.66 GAA (0.45) GAAKMT2ABRD4BPTFALDH1A1
SCHEMBL12497134 0.66 GAA (0.45) GAAKMT2ABRD4BPTFALDH1A1
SCHEMBL19258535 0.66 SLC9A1 (0.46)
SCHEMBL2440360 0.65 GAA (0.38) GAAKMT2ABRD4BPTFALDH1A1
SCHEMBL12294593 0.65
SCHEMBL8544400 0.64 NPC1 (0.64) GAAKMT2ABRD4BPTFALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000993-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO INC (US) 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000993-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME CD44, MSN, AS3MT GAA 36/4885KMT2A 1005/4885BRD4 3709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.