SCHEMBL2483998

SCHEMBL2483998

CC[Si]([O])(CC)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.38
PSIP1 O75475 1/20 0.37
MAPT P10636 3/20 0.35
ESR1 P03372 2/20 0.34
ESR2 Q92731 1/20 0.34
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
ALDH1A1 P00352 3/20 0.33
PPARG P37231 1/20 0.33
BLM P54132 1/20 0.33
NCOA2 Q15596 1/20 0.33
NCOA1 Q15788 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
GLA P06280 1/20 0.32
TSHR P16473 1/20 0.32
NR4A3 Q92570 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6957948 0.80 NAAA (0.36) TP53PSIP1CES2CES1ALDH1A1
SCHEMBL3971800 0.79 MAPT (0.39) TP53PSIP1MAPTESR1ESR2
SCHEMBL6049738 0.77 MAPT (0.38) TP53PSIP1MAPTESR1ESR2
SCHEMBL6963975 0.77 SMN1; SMN2 (0.41) MAPTCES2CES1ALDH1A1NPSR1
SCHEMBL9323038 0.75 TP53 (0.35) TP53PSIP1MAPTESR1ESR2
SCHEMBL6965425 0.75 EPHX2 (0.42) CES2CES1ALDH1A1SMN1; SMN2HPGD
SCHEMBL988676 0.75 NR1H2 (0.43) TP53PSIP1MAPTESR1ESR2
SCHEMBL6972289 0.73 EPHX2 (0.44) CES2CES1ALDH1A1SMN1; SMN2
SCHEMBL2444645 0.72 ESR1 (0.56) TP53PSIP1MAPTESR1ESR2
SCHEMBL3889977 0.72 TP53 (0.41) TP53PSIP1MAPTESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240132675-A1 POLYMER HAVING METAL-OXYGEN-METAL BOND AS PRIMARY CHAIN, COMPOSITION THEREOF, SOLID MATERIAL AND PRODUCTION METHOD THEREOF, AND ELECTRONIC COMPONENT AND FIBER TORAY INDUSTRIES, INC. (JP) 2024-04-25 US disclosed
US-20240002607-A1 POLYMETALLOXANE, COMPOSITION OF SAME, CURED FILM, METHOD OF PRODUCING THE CURED FILM, MEMBER AND ELECTRONIC COMPONENT EACH PROVIDED WITH THE CURED FILM, FIBER, AND METHOD OF PRODUCING THE FIBER TORAY INDUSTRIES, INC. (JP) 2024-01-04 US disclosed
US-11795064-B2 Polymetalloxane, method for producing same, composition thereof, cured film and method for producing same, and members and electronic components provided with same TORAY INDUSTRIES, INC. (JP) 2023-10-24 US disclosed
US-20230331927-A1 POLYMETALLOXANE-CONTAINING COMPOSITION, CURED BODY, MEMBER, ELECTRONIC COMPONENT, AND FIBER TORAY INDUSTRIES, INC. (JP) 2023-10-19 US disclosed
WO-2022202398-A1 POLYMER HAVING METAL-OXYGEN-METAL BOND AS PRIMARY CHAIN, COMPOSITION THEREOF, SOLID MATERIAL AND PRODUCTION METHOD THEREOF, AND ELECTRONIC COMPONENT AND FIBER 東レ株式会社 2022-09-29 WO disclosed
US-20210108339-A1 METHOD FOR PRODUCING METAL OXIDE FIBERS, AND METAL OXIDE FIBERS TORAY INDUSTRIES, INC. (JP) 2021-04-15 US disclosed
EP-3779001-A1 METHOD FOR PRODUCING METAL OXIDE FIBERS, AND METAL OXIDE FIBERS Toray Industries, Inc. (JP) 2021-02-17 EP disclosed
CN-106146851-B Photocurable composition and cured product containing same 信越化学工业株式会社 2020-10-23 CN disclosed
EP-3381969-B1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME TORAY INDUSTRIES (JP) 2020-06-03 EP disclosed
EP-3093303-B1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHINETSU CHEMICAL CO (JP) 2019-08-28 EP disclosed
US-5514419-A POLYDIMETHYLSILOXANE, POLYISOBUTYLENE OLIGOMER DOW CORNING CORPORATION (US) 1996-05-07 US disclosed
US-5508270-A Nucleoside phosphinate compounds and compositions CIBA-GEIGY CORPORATION (US) 1996-04-16 US disclosed
US-5507960-A SURFACE TREATED WITH A BLEND OF A POLYDIMETHYLSILOXANE AND A POLYISOBUTYLENE OLIGOMER; SURFACE GLOSS IS SLIGHTLY ENHANCED DOW CORNING CORPORATION (US) 1996-04-16 US disclosed
EP-0705884-A2 Method for treating plastic, leather or rubber substrates DOW CORNING CORPORATION (US) 1996-04-10 EP disclosed
EP-0705631-A2 Epoxy-terminated polyisobutylene polydimethylsiloxane compositions DOW CORNING CORPORATION (US) 1996-04-10 EP disclosed
EP-0705632-A2 2-Methylpropenyl-terminated polyisobutylene-polydimethyl-siloxane compositions DOW CORNING CORPORATION (US) 1996-04-10 EP disclosed
US-5466677-A Dinucleoside phosphinates and their pharmaceutical compositions CIBA-GEIGY CORPORATION (US) 1995-11-14 US disclosed
US-5442010-A Antifoam agents DOW CORNING CORPORATION (US) 1995-08-15 US disclosed
EP-0614906-A1 Mononucleotide analogues and intermediates therefor CIBA-GEIGY AG (CH) 1994-09-14 EP disclosed
EP-0614907-A1 Dinucleotide and oligonucleotide analogues CIBA-GEIGY AG (CH) 1994-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795064-B2 Polymetalloxane, method for producing same, composition thereof, cured film and method for producing same, and members and electronic components provided with same ASH2L, SETDB1, BMI1 TP53 2420/4885PSIP1 1334/4885MAPT 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.