Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801492 | 1.00 | CHRM2 (0.45) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL27224460 | 0.82 | BTK (0.45) | — | |
| SCHEMBL29131909 | 0.81 | BTK (0.40) | MEN1KMT2AGFER | |
| SCHEMBL29131913 | 0.81 | BTK (0.40) | MEN1KMT2AGFER | |
| SCHEMBL29131884 | 0.79 | IL1B (0.51) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL29131879 | 0.79 | IL1B (0.51) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL30624669 | 0.79 | IL1B (0.51) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL29276170 | 0.78 | PIK3CD (0.46) | — | |
| SCHEMBL29276175 | 0.78 | PIK3CD (0.46) | — | |
| SCHEMBL30493081 | 0.77 | NOS3 (0.49) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881401-A | NLRP3 modulators | 祖玛珍生物科学有限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023278438-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD (US) | 2023-01-05 | — | — | WO | disclosed |