SCHEMBL2484430

SCHEMBL2484430

CCCCOCCOCCOCCOCCOc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.71
RARB P10826 2/20 0.61
KCNA3 P22001 1/20 0.58
TSHR P16473 2/20 0.56
RECQL P46063 1/20 0.56
MLNR O43193 1/20 0.53
NR1I2 O75469 1/20 0.53
ESR1 P03372 1/20 0.53
NR3C1 P04150 1/20 0.53
PGR P06401 1/20 0.53
ADRB2 P07550 1/20 0.53
CHRM2 P08172 1/20 0.53
ADRB1 P08588 1/20 0.53
HTR1A P08908 1/20 0.53
ADRA2A P08913 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
CHRM1 P11229 1/20 0.53
DRD2 P14416 1/20 0.53
ADRA2B P18089 1/20 0.53
ADRA2C P18825 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6558279 1.00 LTA4H (0.71) LTA4HRARBKCNA3TSHRRECQL
SCHEMBL2487712 1.00 LTA4H (0.71) LTA4HRARBKCNA3TSHRRECQL
SCHEMBL2485485 1.00 LTA4H (0.71) LTA4HRARBKCNA3TSHRRECQL
SCHEMBL28049795 0.94 LTA4H (0.70) LTA4HRARBKCNA3TSHRRECQL
SCHEMBL10456457 0.94 LTA4H (0.70) LTA4HRARBKCNA3TSHRRECQL
SCHEMBL7241377 0.94 LTA4H (0.74) LTA4HRARBKCNA3TSHRRECQL
SCHEMBL969026 0.92 LTA4H (0.68) LTA4HRARBKCNA3TSHRMLNR
SCHEMBL9407088 0.92 LTA4H (0.68) LTA4HRARBKCNA3TSHRMLNR
SCHEMBL2485877 0.92 LTA4H (0.68) LTA4HRARBKCNA3TSHRMLNR
SCHEMBL2484231 0.92 LTA4H (0.68) LTA4HRARBKCNA3TSHRMLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110072856-B Process for producing alpha-hydroxycarboxylic acid dimer cyclic ester 株式会社吴羽 2022-03-15 CN disclosed
CN-111699179-B Method for producing cyclic ester 株式会社吴羽 2021-09-17 CN disclosed
CN-111741953-B Method for producing glycolide 株式会社吴羽 2021-05-28 CN disclosed
CN-111757873-A Method for producing glycolide 株式会社吴羽 2020-10-09 CN disclosed
CN-111741953-A Method for producing glycolide 株式会社吴羽 2020-10-02 CN disclosed
CN-111741952-A Method for producing glycolide 株式会社吴羽 2020-10-02 CN disclosed
CN-111699179-A Method for producing cyclic ester 株式会社吴羽 2020-09-22 CN disclosed
WO-2019181340-A1 GLYCOLIDE PRODUCTION METHOD 株式会社クレハ 2019-09-26 WO disclosed
WO-2019181298-A1 METHOD FOR PRODUCING GLYCOLIDE 株式会社クレハ 2019-09-26 WO disclosed
WO-2019181516-A1 GLYCOLIDE PRODUCTION METHOD 株式会社クレハ 2019-09-26 WO disclosed
EP-2377858-B1 METHOD FOR PRODUCING GLYCOLIDE KUREHA CORP (JP) 2014-04-30 EP disclosed
US-20120289713-A1 METHOD FOR PRODUCING GLYCOLIDE KUREHA CORPORATION (JP) 2012-11-15 US disclosed
US-20110263875-A1 Production Process of Glycolide KUREHA CORPORATION (JP) 2011-10-27 US disclosed
EP-2377858-A1 METHOD FOR PRODUCING GLYCOLIDE Kureha Corporation (JP) 2011-10-19 EP disclosed
US-7812181-B2 Process for producing glycolide and glycolic acid oligomer for production of glycolide KUREHA CORPORATION (JP) 2010-10-12 US disclosed
US-20070293653-A1 depolymerizing polyglycolic acid by heating in an organic solvent; system is controlled to suppress efffective concentration of impurities (ammonia, amines or amides, methoxyacetic acid and diglycolic acid); high purity glycolide starting material for polyglycolic acid KUREHA CORPORATION (JP) 2007-12-20 US disclosed
EP-1310496-B1 PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME KUREHA CORP (JP) 2006-12-06 EP disclosed
US-6916939-B2 Process for the preparation of cyclic esters and method for purification of the same KUREHA KAGAKU KOGYO K.K. (JP) 2005-07-12 US disclosed
US-20030191326-A1 Process for the preparation of cyclic esters and method for purification of the same KUREHA CORPORATION (JP) 2003-10-09 US disclosed
EP-1310496-A1 PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191326-A1 Process for the preparation of cyclic esters and method for purification of the same CEL, CETP, MCCC2 LTA4H 908/4885RARB 4616/4885KCNA3 3799/4885
US-20110263875-A1 Production Process of Glycolide RPN2, RPN1, DDOST LTA4H 732/4885RARB 1670/4885KCNA3 4389/4885
US-20120289713-A1 METHOD FOR PRODUCING GLYCOLIDE DDOST, MAGT1, UGCG LTA4H 2545/4885RARB 3243/4885KCNA3 3595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.