SCHEMBL24844368

SCHEMBL24844368

N#Cc1cc(C(F)(F)F)cc2c1ncn2-c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 6/20 0.40
▸ SRC P12931 3/20 0.40
▸ HTT P42858 1/20 0.40
▸ GABRA1 P14867 1/20 0.39
▸ GABRG2 P18507 1/20 0.39
▸ GABRB3 P28472 1/20 0.39
▸ GABRA5 P31644 1/20 0.39
▸ GABRA3 P34903 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21361137 0.81 FGFR1 (0.49) FGFR1SRCHTTALDH1A1
SCHEMBL17940706 0.78 HTT (0.51) FGFR1SRCHTTGABRA1GABRG2
SCHEMBL24844327 0.75 FGFR1 (0.50) FGFR1SRCHTTALDH1A1
SCHEMBL29642847 0.71 GABRA1 (0.49) FGFR1SRCHTTGABRA1GABRG2
SCHEMBL17940732 0.71 GABRA1 (0.49) FGFR1SRCHTTGABRA1GABRG2
SCHEMBL17940725 0.71 FGFR1 (0.59) FGFR1SRCHTTALDH1A1
SCHEMBL19848423 0.71 HTT (0.59) FGFR1SRCHTTALDH1A1
SCHEMBL25121375 0.69 FGFR1 (0.42) FGFR1SRCHTT
SCHEMBL19915930 0.68 FGFR1 (0.62) FGFR1SRCHTTALDH1A1
SCHEMBL1761803 0.67 GABRA1 (0.78) FGFR1GABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230006152-A1 METAL COMPLEX AND LIGHT EMITTING DEVICE CITY UNIVERSITY OF HONG KONG (HK) 2023-01-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230006152-A1 METAL COMPLEX AND LIGHT EMITTING DEVICE OCIAD1, OCIAD2, OPRD1 FGFR1 4472/4885SRC 3518/4885HTT 2976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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