SCHEMBL24844709

SCHEMBL24844709

O=C(OCCCOc1ccccc1)c1ncc[nH]1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 3/20 0.51
MMP2 P08253 2/20 0.51
MMP9 P14780 2/20 0.51
MMP1 P03956 2/20 0.49
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
KCNA3 P22001 1/20 0.42
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24844707 0.86 NPC1 (0.42) MMP12MMP2MMP9MMP1NPC1
SCHEMBL29045186 0.79 NPC1 (0.38) MMP12MMP2MMP9NPC1RAB9A
SCHEMBL2421526 0.79 LMNA (0.54) NPC1RAB9AALDH1A1SMN1; SMN2HSD17B10
SCHEMBL11836426 0.79 KMT2A (0.47) NPC1RAB9AKMT2AKDM4EALDH1A1
SCHEMBL564394 0.78 NPC1 (0.38) MMP12MMP2MMP9NPC1RAB9A
SCHEMBL1961672 0.78 LMNA (0.49) MMP12MMP2MMP9MMP1NPC1
SCHEMBL432658 0.78 TDP1 (0.53) MMP12MMP2MMP9MMP1RAB9A
SCHEMBL9738958 0.77 LMNA (0.50) MMP2NPC1RAB9AKDM4EALDH1A1
SCHEMBL8863229 0.77 LMNA (0.50) MMP2NPC1RAB9AKDM4EALDH1A1
SCHEMBL7402248 0.76 ALOX15 (0.50) NPC1RAB9AKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002679-A1 COMPOUND AND LIQUID CRYSTAL COMPOSITION FUJIFILM CORPORATION (JP) 2023-01-05 US disclosed