SCHEMBL24846320

SCHEMBL24846320

CCCCCNc1cc[nH]c(=O)c1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 11/20 0.47
ABL1 P00519 1/20 0.45
AR P10275 1/20 0.44
ADRA2A P08913 1/20 0.43
EPHX1 P07099 1/20 0.40
ELANE P08246 2/20 0.40
SCN8A Q9UQD0 1/20 0.39
SCN10A Q9Y5Y9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23133056 0.81 SCN8A (0.43) GPR84ARADRA2ASCN8ASCN10A
SCHEMBL8134030 0.74 EPHX1 (0.64) ABL1EPHX1
SCHEMBL3662823 0.72 ABL1 (0.54) ABL1ADRA2AEPHX1
SCHEMBL4893047 0.72 ABL1 (0.42) GPR84ABL1ADRA2A
SCHEMBL3400985 0.71 ADRA2A (0.53) GPR84ABL1ADRA2AEPHX1
SCHEMBL1241959 0.71 ABL1 (0.56) ABL1ADRA2ASCN8A
SCHEMBL24517467 0.70
SCHEMBL28317581 0.70 ADRA2A (0.47) GPR84ABL1ARADRA2A
SCHEMBL606375 0.70 ELANE (0.46) GPR84ELANE
SCHEMBL11498100 0.69 ABL1 (0.59) ABL1ADRA2AEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000773-A1 NOVEL HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000773-A1 NOVEL HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PEBP1, PLTP GPR84 3400/4885ABL1 4124/4885AR 3883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.