Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18692612 | 1.00 | SLC6A1 (0.36) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL20744258 | 1.00 | SLC6A1 (0.36) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL1470518 | 0.85 | SLC6A1 (0.36) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL20744262 | 0.85 | SLC6A1 (0.36) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL20136819 | 0.85 | SLC6A1 (0.36) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL27198371 | 0.85 | SLC6A1 (0.36) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL3579211 | 0.85 | PARP1 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL1033901 | 0.85 | PARP1 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3582591 | 0.85 | PARP1 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3816058 | 0.83 | SLC6A1 (0.37) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677726-A | KRAS inhibitors | 百时美施贵宝公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-112939967-B | Pyrazolo [1,5-a ] pyridine compound, and preparation method and application thereof | 深圳众格生物科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-114787161-B | Pyrazolo [1,5-a ] pyridine compound, and preparation method and application thereof | 深圳众格生物科技有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-114787161-A | Pyrazolo [1,5-a ] pyridine compound and preparation method and application thereof | 深圳众格生物科技有限公司 | 2022-07-22 | — | — | CN | disclosed |
| WO-2021115457-A9 | PYRAZOLO[1,5-A]PYRIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳众格生物科技有限公司 | 2022-05-19 | — | — | WO | disclosed |
| US-20180028508-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RES INC (US) | 2018-02-01 | — | — | US | disclosed |
| US-20170101405-A1 | N-SULFONYLATED PYRAZOLO[3,4-b]PYRIDIN-6-CARBOXAMIDES AND METHOD OF USE | ABBVIE S.Á.R.L. (LU) | 2017-04-13 | — | — | US | disclosed |
| US-20160304516-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | Quanticel Pharmaceuticals, Inc. | 2016-10-20 | — | — | US | disclosed |
| EP-2780342-A1 | AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE | Sunshine Lake Pharma Co., Ltd. (CN) | 2014-09-24 | — | — | EP | disclosed |
| CN-101868464-B | Thienopyrimidiene derivatives as PI3k inhibitors | HOFFMANN LA ROCHE | 2013-11-13 | — | — | CN | disclosed |
| WO-2013071697-A1 | AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2013-05-23 | — | — | WO | disclosed |
| US-8097626-B2 | IL-8 receptor antagonists | GLAXOSMITHKLINE LLC (US) | 2012-01-17 | — | — | US | disclosed |
| CN-101868464-A | Thienopyrimidiene derivatives as PI3k inhibitors | HOFFMANN LA ROCHE | 2010-10-20 | — | — | CN | disclosed |
| US-20090298810-A1 | IL-8 Receptor Antagonists | SMITHKLINE BEECHAM CORPORATION | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101405-A1 | N-SULFONYLATED PYRAZOLO[3,4-b]PYRIDIN-6-CARBOXAMIDES AND METHOD OF USE | CFTR, P2RY1, P2RX5 | SLC6A1 2828/4885GABRA5 2261/4885GABRB2 2679/4885 |
| US-20180028508-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | KDM1B, KDM1A, KDM3A | SLC6A1 4080/4885GABRA5 2666/4885GABRB2 2155/4885 |
| US-20090298810-A1 | IL-8 Receptor Antagonists | CXCL8, CCR8, IL1RN | SLC6A1 3880/4885GABRA5 544/4885GABRB2 656/4885 |
| US-20160304516-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | KDM1B, KDM1A, KDM3A | SLC6A1 4080/4885GABRA5 2666/4885GABRB2 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.