SCHEMBL2484929

SCHEMBL2484929

Brc1cc(Br)cc(-c2nc3ccccc3n2-c2ccccc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 4/20 0.57
ESR1 P03372 3/20 0.57
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.54
HDAC1 Q13547 3/20 0.50
HDAC8 Q9BY41 3/20 0.50
HDAC6 Q9UBN7 3/20 0.50
RECQL P46063 1/20 0.50
PRKACA P17612 1/20 0.49
RPS6KB1 P23443 1/20 0.49
GSK3B P49841 1/20 0.49
ROCK1 Q13464 1/20 0.49
GRIA1 P42261 1/20 0.49
CACNG8 Q8WXS5 1/20 0.49
CACNG2 Q9Y698 1/20 0.49
GSR P00390 1/20 0.45
PTGS2 P35354 1/20 0.44
MAPT P10636 3/20 0.44
TSHR P16473 2/20 0.43
LMNA P02545 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14995314 0.97 ESR2 (0.57) ESR2ESR1MAPK1HTTHDAC1
SCHEMBL13893897 0.90 ESR2 (0.55) ESR2ESR1MAPK1HTTHDAC1
SCHEMBL3257779 0.89 ESR2 (0.66) ESR2ESR1MAPK1HTTHDAC1
SCHEMBL64508 0.89 ESR2 (0.66) ESR2ESR1MAPK1HTTHDAC1
SCHEMBL29351258 0.89 ESR2 (0.66) ESR2ESR1MAPK1HTTHDAC1
SCHEMBL338639 0.88 ESR1 (0.58) ESR2ESR1MAPK1HTTHDAC1
SCHEMBL25453878 0.88 ESR2 (0.49) ESR2ESR1MAPK1HTTHDAC1
SCHEMBL28153332 0.88 ESR1 (0.61) ESR2ESR1MAPK1HTTHDAC1
SCHEMBL16116629 0.87 ESR1 (0.55) ESR2ESR1MAPK1HTTHDAC1
SCHEMBL6257624 0.87 ESR2 (0.64) ESR2ESR1MAPK1HTTHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038143-B2 Polymer compound, material for electronic elements, material for organic electroluminescent elements, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-07-31 US disclosed
US-9530970-B2 Benzimidazole compound, organic photoelectric device including the same, and display element including the same CHEIL INDUSTRIES, INC. (KR) 2016-12-27 US disclosed
US-9530970-B2 Benzimidazole compound, organic photoelectric device including the same, and display element including the same CHEIL INDUSTRIES, INC. (KR) 2016-12-27 US disclosed
EP-2197979-B1 NOVEL COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL IND INC (KR) 2016-12-07 EP disclosed
EP-2197979-B1 NOVEL COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL IND INC (KR) 2016-12-07 EP disclosed
US-20150249215-A1 POLYMER COMPOUND, MATERIAL FOR ELECTRONIC ELEMENTS, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-03 US disclosed
EP-2377907-B1 NOVEL COMPOUNDS FOR AN ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE COMPRISING SAME CHEIL IND INC (KR) 2014-12-03 EP disclosed
US-8772632-B2 Compound for organic photoelectric device, organic photoelectric device including the same, and display device including the same CHEIL INDUSTRIES, INC. (KR) 2014-07-08 US disclosed
US-8772632-B2 Compound for organic photoelectric device, organic photoelectric device including the same, and display device including the same CHEIL INDUSTRIES, INC. (KR) 2014-07-08 US disclosed
US-8772632-B2 Compound for organic photoelectric device, organic photoelectric device including the same, and display device including the same CHEIL INDUSTRIES, INC. (KR) 2014-07-08 US disclosed
US-20110260153-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-10-27 US disclosed
US-20110260153-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-10-27 US disclosed
EP-2377907-A2 NOVEL COMPOUNDS FOR AN ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE COMPRISING SAME Cheil Industries Inc. (KR) 2011-10-19 EP disclosed
US-20100200054-A1 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-08-12 US disclosed
US-20100200054-A1 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-08-12 US disclosed
US-20100200054-A1 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-08-12 US disclosed
WO-2010076991-A2 NOVEL COMPOUNDS FOR AN ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE COMPRISING SAME 제일모직 주식회사 (KR) 2010-07-08 WO disclosed
EP-2197979-A2 NOVEL COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME Cheil Industries Inc. (KR) 2010-06-23 EP disclosed
WO-2010044607-A1 BENZIMIDAZOLE COMPOUNDS AND ORGANIC PHOTOELECTRIC DEVICE WITH THE SAME CHEIL INDUSTRIES INC. (KR) 2010-04-22 WO disclosed
WO-2009051454-A2 NOVEL COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES INC. (KR) 2009-04-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110260153-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME PPOX, AOX1, OR10J3 ESR2 2206/4885ESR1 152/4885MAPK1 147/4885
US-20100200054-A1 Compound for organic photoelectric device and organic photoelectric device including the same PPOX, PIEZO1, AOX1 ESR2 1194/4885ESR1 141/4885MAPK1 302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.