SCHEMBL338639

SCHEMBL338639

Brc1cccc(-c2nc3ccccc3n2-c2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.58
ESR2 Q92731 1/20 0.58
MAPT P10636 4/20 0.58
HDAC1 Q13547 3/20 0.57
HDAC8 Q9BY41 3/20 0.57
HDAC6 Q9UBN7 3/20 0.57
LMNA P02545 2/20 0.56
TSHR P16473 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MAPK1 P28482 1/20 0.55
HTT P42858 1/20 0.55
RECQL P46063 1/20 0.48
CFTR P13569 1/20 0.47
PRKACA P17612 1/20 0.47
RPS6KB1 P23443 1/20 0.47
GSK3B P49841 1/20 0.47
ROCK1 Q13464 1/20 0.47
GRIA1 P42261 1/20 0.47
CACNG8 Q8WXS5 1/20 0.47
CACNG2 Q9Y698 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466073 0.97 ESR1 (0.56) ESR1ESR2MAPTHDAC1HDAC8
SCHEMBL15154977 0.97 ESR1 (0.56) ESR1ESR2MAPTHDAC1HDAC8
SCHEMBL16116629 0.93 ESR1 (0.55) ESR1ESR2MAPTHDAC1HDAC8
SCHEMBL16116627 0.93 ESR1 (0.58) ESR1ESR2MAPTHDAC1HDAC8
SCHEMBL8512875 0.91 ESR1 (0.58) ESR1ESR2MAPTHDAC1HDAC8
SCHEMBL13314056 0.89 ESR2 (0.67) ESR1ESR2MAPTHDAC1HDAC8
SCHEMBL14995314 0.88 ESR2 (0.57) ESR1ESR2MAPTHDAC1HDAC8
SCHEMBL2484929 0.88 ESR2 (0.57) ESR1ESR2MAPTHDAC1HDAC8
SCHEMBL28710311 0.88 HDAC1 (0.50) ESR1ESR2MAPTHDAC1HDAC8
SCHEMBL29466033 0.88 HDAC1 (0.50) ESR1ESR2MAPTHDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106905242-B The two poles of the earth configuration pyrenyl containing benzimidazole unit blue light material and preparation method and application 中国矿业大学 2019-07-12 CN claimed
CN-106905242-A The two poles of the earth configuration pyrenyl containing benzimidazole unit blue light material and preparation method and application 中国矿业大学 2017-06-30 CN claimed
CN-103524497-B Bipolarity phosphorescence host compound, preparation method and application and electroluminescent device TCL GROUP CO., LTD. (CN) 2015-08-05 CN claimed
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-12018022-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode LT MATERIALS CO., LTD. (KR) 2024-06-25 US disclosed
US-12018022-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode LT MATERIALS CO., LTD. (KR) 2024-06-25 US disclosed
US-11827623-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode LT MATERIALS CO., LTD. (KR) 2023-11-28 US disclosed
US-11827623-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode LT MATERIALS CO., LTD. (KR) 2023-11-28 US disclosed
EP-3880682-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-14 EP disclosed
CN-116082369-A Organic electroluminescent material based on triazolopyridine and organic electroluminescent device 武汉尚赛光电科技有限公司 2023-05-09 CN disclosed
US-7851071-B2 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2010-12-14 US disclosed
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD, (JP) 2010-08-05 US disclosed
WO-2009148269-A9 BENZOFLUORANTHENE DERIVATIVE AND AN ORGANIC LUMINESCENT ELEMENT EMPLOYING THE SAME 주식회사 두산 (KR) 2010-04-22 WO disclosed
EP-2174932-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
EP-2174933-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
WO-2009148269-A2 BENZOFLUORANTHENE DERIVATIVE AND AN ORGANIC LUMINESCENT ELEMENT EMPLOYING THE SAME 주식회사 두산 (KR) 2009-12-10 WO disclosed
US-20090134783-A1 Materials for organic light-emitting diodes ACADEMIA SINICA (TW) 2009-05-28 US disclosed
US-20060147747-A1 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2006-07-06 US disclosed
EP-1602648-A1 NITROGEN-CONTAINING HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12018022-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode ODC1, AOX1, CYP1B1 ESR1 384/4885ESR2 1451/4885MAPT 1022/4885
US-20090134783-A1 Materials for organic light-emitting diodes EML4, CRY1, CRY2 ESR1 27/4885ESR2 101/4885MAPT 144/4885
US-11827623-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode ODC1, CYP1B1, CYP1A1 ESR1 334/4885ESR2 1215/4885MAPT 1067/4885
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same NSD1, EED, ERG ESR1 77/4885ESR2 489/4885MAPT 2292/4885
US-12035625-B2 Materials for organic electroluminescent devices ZYX, RER1, AOC2 ESR1 259/4885ESR2 30/4885MAPT 4261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.