Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24849557 | 0.85 | ALDH1A1 (0.38) | MIFALDH1A1L3MBTL1TRPA1SMN1; SMN2 | |
| SCHEMBL15131812 | 0.83 | MIF (0.43) | MIFALDH1A1L3MBTL1SMN1; SMN2ATM | |
| SCHEMBL8396488 | 0.82 | ACHE (0.45) | MIFALDH1A1L3MBTL1SMN1; SMN2ATM | |
| SCHEMBL10814385 | 0.80 | MIF (0.41) | MIFALDH1A1L3MBTL1SMN1; SMN2ATM | |
| SCHEMBL28077941 | 0.80 | LMNA (0.46) | MIFALDH1A1L3MBTL1SMN1; SMN2ATM | |
| SCHEMBL5834129 | 0.80 | SMN1; SMN2 (0.61) | ALDH1A1L3MBTL1TRPA1SMN1; SMN2ATM | |
| SCHEMBL7394143 | 0.78 | ALDH1A1 (0.43) | MIFALDH1A1L3MBTL1SMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL7313530 | 0.78 | LMNA (0.49) | MIFALDH1A1L3MBTL1SMN1; SMN2ATM | |
| SCHEMBL16837505 | 0.78 | MIF (0.40) | MIFALDH1A1L3MBTL1SMN1; SMN2ATM | |
| SCHEMBL16837504 | 0.77 | L3MBTL1 (0.44) | MIFALDH1A1L3MBTL1SMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274258-A1 | HETEROATOM-SUBSTITUTED AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川大学华西医院 | 2023-01-05 | — | — | WO | disclosed |