Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780943 | 0.78 | TAAR1 (0.39) | TAAR1SLC6A2SLC6A4MAOASLC6A3 | |
| SCHEMBL68908 | 0.74 | TSHR (0.38) | TAAR1SLC6A2SLC6A4MAOASLC6A3 | |
| SCHEMBL28604611 | 0.74 | TAAR1 (0.36) | TAAR1SLC6A2SLC6A4MAOASLC6A3 | |
| SCHEMBL7363533 | 0.74 | TAAR1 (0.36) | TAAR1SLC6A2SLC6A4MAOASLC6A3 | |
| SCHEMBL5420712 | 0.71 | MAPT (0.35) | TAAR1TDP1 | |
| SCHEMBL29404135 | 0.70 | TAAR1 (0.33) | TAAR1MAOAAOC3TDP1MAOB | |
| SCHEMBL10001848 | 0.70 | TRPA1 (0.38) | TAAR1SLC6A2SLC6A4MAOASLC6A3 | |
| SCHEMBL28400171 | 0.69 | POLB (0.39) | TAAR1RIPK1 | |
| SCHEMBL10318392 | 0.69 | TSHR (0.33) | TAAR1SLC6A2SLC6A4SLC6A3RIPK1 | |
| SCHEMBL31590180 | 0.69 | ALDH1A1 (0.33) | TAAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023277824-A2 | DIVERSE FUNCTIONALIZATION OF HYDROSILANES AND PROGRAMMABLE SYNTHESIS OF MULTISUBSTITUTED ORGANOSILANES ENABLED BY NEUTRAL EOSIN Y PHOTOCATALYSIS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-01-05 | — | — | WO | disclosed |