SCHEMBL780943

SCHEMBL780943

CC(C)[SiH2]c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.39
TDP1 Q9NUW8 1/20 0.36
AOC3 Q16853 2/20 0.34
MAOA P21397 2/20 0.34
MAOB P27338 1/20 0.34
SLC6A2 P23975 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
TRPA1 O75762 2/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
CYP2A6 P11509 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
RIPK1 Q13546 1/20 0.33
ADRA2A P08913 1/20 0.32
ADRA2C P18825 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706914 0.84
SCHEMBL24849720 0.78 TAAR1 (0.36) TAAR1TDP1AOC3MAOAMAOB
SCHEMBL28604611 0.78 TAAR1 (0.36) TAAR1TDP1AOC3MAOAMAOB
SCHEMBL7363533 0.78 TAAR1 (0.36) TAAR1TDP1AOC3MAOAMAOB
SCHEMBL68908 0.78 TSHR (0.38) TAAR1TDP1AOC3MAOAMAOB
SCHEMBL5420712 0.75 MAPT (0.35) TAAR1TDP1LMNATSHRALOX12
SCHEMBL10001848 0.74 TRPA1 (0.38) TAAR1AOC3MAOAMAOBSLC6A2
SCHEMBL29404135 0.74 TAAR1 (0.33) TAAR1TDP1AOC3MAOAMAOB
SCHEMBL4162555 0.73 TAAR1 (0.35) TAAR1TDP1AOC3MAOAMAOB
SCHEMBL31590180 0.72 ALDH1A1 (0.33) TAAR1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106188547-B A kind of organosilicon damping additive and preparation method thereof 山东大学 2019-02-01 CN claimed
EP-1971664-B1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2015-09-09 EP claimed
US-7919196-B2 Emitting materials and organic light emitting device using the same LG CHEM, LTD. (KR) 2011-04-05 US claimed
US-20090021149-A1 Emitting Materials and Organic Light Emitting Device Using the Same LG CHEM. LTD. (KR) 2009-01-22 US claimed
EP-1971664-A1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG Chem, Ltd. (KR) 2008-09-24 EP claimed
WO-2007081179-A1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM. LTD. (KR) 2007-07-19 WO claimed
CN-114207038-B Resin composition, method for producing cured product, pattern cured product, interlayer insulating film, covercoat, surface protective film, and electronic component 艾曲迪微系统股份有限公司 2024-03-22 CN disclosed
CN-116969986-A 1, 4-silazane heterocyclic compound and synthesis method and application thereof 四川大学 2023-10-31 CN disclosed
CN-114207038-A Resin composition, method for producing cured product, patterned cured product, interlayer insulating film, covercoat, surface protective film, and electronic component 艾曲迪微系统股份有限公司 2022-03-18 CN disclosed
US-10626099-B2 Process for preparing pleuromutilin CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2020-04-21 US disclosed
CN-110256327-A A kind of method of iron catalysis oxidation Benzazole compounds synthesis 2- indole ketone compound 南京师范大学 2019-09-20 CN disclosed
CN-109715680-A The method for preparing high-cis -1,4- polydiene with the carbon monoxide-olefin polymeric based on lanthanide series 株式会社普利司通 2019-05-03 CN disclosed
CN-103988127-B Photosensitive resin composition, method for producing cured relief pattern, semiconductor device, and display device 旭化成株式会社 2019-04-19 CN disclosed
US-20050053792-A1 High purity; using supercritical fluid; high temperature; high pressure; polyolefins; interface film for glass; ceramic binder SEKISUI CHEMICAL CO., LTD. (JP) 2005-03-10 US disclosed
EP-1501821-A1 NEW ORGANIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LG Chem, Ltd. (KR) 2005-02-02 EP disclosed
EP-1452549-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO., LTD. (JP) 2004-09-01 EP disclosed
US-20040067387-A1 Organic compounds for electroluminescence and organic electroluminescent devices using the same LG CHEM. LTD. (KR) 2004-04-08 US disclosed
WO-2003095445-A1 NEW ORGANIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LG CHEM, LTD. (KR) 2003-11-20 WO disclosed
US-6471955-B1 POLYSTYRENES AS PREFERENTIAL TIME-RELEASE AGENTS OR CARRIERS OF PROSTAGLANDINS SUCH AS MISOPROSTOL USED FOR PREVENTION OF PEPTIC ULCERS PHARMACIA CORPORATION 2002-10-29 US disclosed
WO-1998044952-A1 pH-SELECTIVE DELIVERY SYSTEM USING CROSS-LINKED POLYMERIC RESINS AS VEHICLES MONSANTO COMPANY (US) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626099-B2 Process for preparing pleuromutilin PLEC, MLN, MRPL21 TAAR1 3035/4885TDP1 3570/4885AOC3 4040/4885
US-20090021149-A1 Emitting Materials and Organic Light Emitting Device Using the Same CRY1, CRY2, PER2 TAAR1 2262/4885TDP1 2524/4885AOC3 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.