Arginine

Arginine

SCHEMBL2485033

N=C(N)NCCCC(N)C(=O)O.NOC(=O)c1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACES1PR1S1PR4S1PR5

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OTC P00480 1/20 0.43
SLC1A5 Q15758 1/20 0.39
POLB P06746 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
PRSS1 P07477 2/20 0.38
TMPRSS15 P98073 2/20 0.38
DDAH1 O94760 1/20 0.38
DPP7 Q9UHL4 1/20 0.37
SLC7A5 Q01650 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
KIF11 P52732 3/20 0.37
LTA4H P09960 1/20 0.37
C3AR1 Q16581 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL4606882 0.87 F10 (0.44) OTCPOLBKMT2ATDP1PRSS1
Arginine SCHEMBL12006798 0.87 OTC (0.43) OTCPOLBKMT2ATDP1DDAH1
Arginine SCHEMBL4606883 0.87 F10 (0.44) OTCPOLBKMT2ATDP1PRSS1
Arginine SCHEMBL1287134 0.87 OTC (0.43) OTCPOLBKMT2ATDP1DDAH1
Arginine SCHEMBL7766336 0.87 CASR (0.45) OTCSLC1A5KMT2APRSS1TMPRSS15
Arginine SCHEMBL28911625 0.86 OTC (0.43) OTCPOLBKMT2ATDP1DDAH1
Arginine SCHEMBL28268971 0.84 OTC (0.53) OTCKMT2ADDAH1
Arginine SCHEMBL28911624 0.84 OTC (0.41) OTCPOLBKMT2ATDP1PRSS1
Arginine SCHEMBL31315051 0.84 CA2 (0.44) OTCPOLBKMT2ATDP1DDAH1
SCHEMBL2246952 0.84 NPY4R (0.39) OTCSLC1A5POLBKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170304187-A1 EMU Oil In Combination With Other Active Ingredients For Treating Skin Imperfections DESAI, KETAN 2017-10-26 US claimed
US-20220409518-A1 EMU Oil In Combination With Other Active Ingredients For Treating Skin Imperfections DESAI, KETAN 2022-12-29 US disclosed
CN-112088010-A Compositions and methods for treating vaginal dryness 宝洁公司 2020-12-15 CN disclosed
EP-3366274-A1 COSMETIC BIOPHOTONIC COMPOSITIONS KLOX Technologies, Inc. (CA) 2018-08-29 EP disclosed
US-20170326378-A1 COSMETIC BIOPHOTONIC COMPOSITIONS KLOX TECHNOLOGIES INC. (CA) 2017-11-16 US disclosed
US-20170304187-A1 EMU Oil In Combination With Other Active Ingredients For Treating Skin Imperfections DESAI, KETAN 2017-10-26 US disclosed
US-9757324-B2 Emu oil in combination with other active ingredients for treating skin imperfections DESAI, KETAN 2017-09-12 US disclosed
EP-3178467-A1 COSMETIC BIOPHOTONIC COMPOSITIONS KLOX Technologies, Inc. (CA) 2017-06-14 EP disclosed
US-20160184215-A1 EMU OIL IN COMBINATION WITH OTHER ACTIVE INGREDIENTS FOR TREATING SKIN IMPERFECTIONS DESAI, KETAN 2016-06-30 US disclosed
EP-2379082-B1 ACNE TREATMENT POWDER FOUNDATION EI INC (US) 2016-02-10 EP disclosed
EP-1196139-A1 SHEET-LIKE DEVICES THE PROCTER & GAMBLE COMPANY (US) 2002-04-17 EP disclosed
US-6338855-B1 DISPOSABLE CLEANING SHEETS WITH FROTHS AND SURFACTANTS THE PROCTER & GAMBLE COMPANY 2002-01-15 US disclosed
WO-2001001952-A1 DEVICES THE PROCTER & GAMBLE COMPANY (US) 2001-01-11 WO disclosed
WO-2001002477-A1 PRE-FORMED, SELF-ADHESIVE SHEETS SUITABLE FOR TOPICAL APPLICATION THE PROCTER & GAMBLE COMPANY (US) 2001-01-11 WO disclosed
WO-2001001951-A1 SHEET-LIKE DEVICES THE PROCTER & GAMBLE COMPANY (US) 2001-01-11 WO disclosed
WO-2001001933-A2 PRE-FORMED, SELF-ADHESIVE SHEET DEVICES SUITABLE FOR TOPICAL APPLICATION THE PROCTER & GAMBLE COMPANY (US) 2001-01-11 WO disclosed
WO-2001002028-A2 PRE-FORMED, SHEET DEVICES SUITABLE FOR TOPICAL APPLICATION THE PROCTER & GAMBLE COMPANY (US) 2001-01-11 WO disclosed
WO-2001002479-A1 PRE-FORMED, SELF-ADHESIVE SHEET DEVICES SUITABLE FOR TOPICAL APPLICATION THE PROCTER & GAMBLE COMPANY (US) 2001-01-11 WO disclosed
WO-2001002478-A1 PRE-FORMED, SELF-ADHESIVE SHEET DEVICES SUITABLE FOR TOPICAL APPLICATION THE PROCTER & GAMBLE COMPANY (US) 2001-01-11 WO disclosed
WO-2001001816-A1 COSMETIC OR DERMAPHARMACEUTICAL PATCH PROCTER & GAMBLE COMPANY (US) 2001-01-11 WO disclosed