Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 4/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL12006798 | 1.00 | OTC (0.43) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL28911625 | 0.99 | OTC (0.43) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL4606882 | 0.92 | F10 (0.44) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL4606883 | 0.92 | F10 (0.44) | OTCPOLBKMT2ATDP1DDAH1 | |
| L-Citrulline SCHEMBL31412709 | 0.89 | C3AR1 (0.46) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL28268971 | 0.88 | OTC (0.53) | OTCKMT2ADDAH1NOS3NOS1 | |
| Arginine SCHEMBL31315051 | 0.88 | CA2 (0.44) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL28911606 | 0.88 | OTC (0.41) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL28911624 | 0.88 | OTC (0.41) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL26914670 | 0.87 | KIF11 (0.46) | OTCPOLBKMT2ATDP1DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2624689-A2 | ANTIMICROBIAL PACKAGING MATERIAL AND METHODS OF MAKING AND USING THE SAME | Cryovac, Inc. (US) | 2013-08-14 | — | — | EP | claimed |
| WO-2012047947-A2 | ANTIMICROBIAL PACKAGING MATERIAL AND METHODS OF MAKING AND USING THE SAME | CRYOVAC, INC. (US) | 2012-04-12 | — | — | WO | claimed |
| US-12409121-B2 | Formulations and methods for preparing stable cosmetic compositions | Spinart, LLC (US) | 2025-09-09 | — | — | US | disclosed |
| EP-3802122-A1 | METHOD OF MAKING AN ANTIMICROBIAL MULTILAYER FILM | Cryovac, LLC (US) | 2021-04-14 | — | — | EP | disclosed |
| US-20200352840-A1 | FORMULATIONS AND METHODS FOR PREPARING STABLE COSMETIC COMPOSITIONS | Spinart, LLC | 2020-11-12 | — | — | US | disclosed |
| EP-3302707-A1 | URINE METABOLITE PROFILES IDENTIFY KIDNEY ALLOGRAFT STATUS | Cornell University (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016196329-A1 | URINE METABOLITE PROFILES IDENTIFY KIDNEY ALLOGRAFT STATUS | CORNELL UNIVERSITY (US) | 2016-12-08 | — | — | WO | disclosed |
| US-20130109636-A1 | TRI-AMINO RELEASING FULVATE | SCHUTT STEVEN R (US) | 2013-05-02 | — | — | US | disclosed |
| WO-2012118532-A1 | A TRI AMINO RELEASING FULVATE | SCHUTT STEVEN R (US) | 2012-09-07 | — | — | WO | disclosed |
| US-20120220752-A1 | TRI-AMINO RELEASING FULVATE | SCHUTT STEVEN R (US) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220752-A1 | TRI-AMINO RELEASING FULVATE | DAO, PAM, SLC1A5 | OTC 1117/4885POLB 890/4885KMT2A 2725/4885 |
| US-20130109636-A1 | TRI-AMINO RELEASING FULVATE | DAO, AADAT, FGB | OTC 3131/4885POLB 2545/4885KMT2A 2152/4885 |
| US-12409121-B2 | Formulations and methods for preparing stable cosmetic compositions | CUTA, ARG1, ODC1 | OTC 4/4885POLB 1583/4885KMT2A 2576/4885 |
| US-20200352840-A1 | FORMULATIONS AND METHODS FOR PREPARING STABLE COSMETIC COMPOSITIONS | CUTA, ARG1, ODC1 | OTC 4/4885POLB 1583/4885KMT2A 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.